A comprehensive and systemic review of ginseng-based nanomaterials: Synthesis, targeted delivery, and biomedical applications
Reviewartikel, 2023

Among 17 Panax species identified across the world, Panax ginseng (Korean ginseng), Panax quinquefolius (American ginseng), and Panax notoginseng (Chinese ginseng) are highly recognized for the presence of bioactive compound, ginsenosides and their pharmacological effects. P. ginseng is widely used for synthesis of different types of nanoparticles compared to P. quinquefolius and P. notoginseng. The use of nano-ginseng could increase the oral bioavailability, membrane permeability, and thus provide effective delivery of ginsenosides to the target sites through transport system. In this review, we explore the synthesis of ginseng nanoparticles using plant extracts from various organs, microbes, and polymers, as well as their biomedical applications. Furthermore, we highlight transporters involved in transport of ginsenoside nanoparticles to the target sites. Size, zeta potential, temperature, and pH are also discussed as the critical parameters affecting the quality of ginseng nanoparticles synthesis.

ginsenoside based nanoparticles

ginseng nanoparticle synthesis

targeted delivery

biomedical applications

polymer-based ginsenoside nanocarrier

Panax species

green synthesis

microbial synthesis

Författare

Sri Renukadevi Balusamy

Sejong University

Haribalan Perumalsamy

Hanyang University

Md Amdadul Huq

Chung-Ang University

Tae Hyun Yoon

Hanyang University

Ivan Mijakovic

Chalmers, Life sciences, Systembiologi

Danmarks Tekniske Universitet (DTU)

Lakshmi Thangavelu

Saveetha Dental College And Hospitals

Deok Chun Yang

Kyung Hee University

Shadi Rahimi

Chalmers, Life sciences, Systembiologi

Medicinal Research Reviews

0198-6325 (ISSN) 1098-1128 (eISSN)

Vol. 43 5 1374-1410

Utveckling av grafenbaserad antibakteriell yta för medicintekniska produkter - Effektiv, säker och prisvärd

VINNOVA (2020-00792), 2020-06-01 -- 2022-05-31.

Ämneskategorier

Oorganisk kemi

Botanik

Organisk kemi

DOI

10.1002/med.21953

PubMed

36939049

Mer information

Senast uppdaterat

2024-03-07