The influence of sac centreline on saccular aneurysm rupture: computational study
Artikel i vetenskaplig tidskrift, 2023

The geometric characteristics of a saccular aneurysm play a crucial role in its rupturing. This article thoroughly investigates the impact of the sac centerline on aneurysm rupture, with a focus on identifying significant factors related to rupture at different time intervals. The study employs comprehensive computational simulations of six models of the ICA with varying coiling porosities and blood HCTs, using CFD analysis to examine WSS, OSI, pressure, and velocity within the saccular aneurysm for different sac centerlines. The results indicate that higher blood HCT levels lead to increased WSS and pressure values on the aneurysm wall, while OSI and mean velocity decrease. The study also reveals that coiling techniques can significantly reduce the risk of rupture, as decreasing coil porosity (increasing coil permeability) increases OSI and pressure while decreasing WSS and blood velocity within the aneurysm sac.

Författare

Hao Jiang

Hangzhou First People's Hospital

Zhiwei Lu

Hangzhou Heyunjia Hospital

M. Barzegar Gerdroodbary

Babol Noshirvani University of Technology (BNUT)

Amir Sabernaeemi

Student vid Chalmers

Sajad Salavatidezfouli

Scuola Internazionale Superiore di Studi Avanzati

Scientific Reports

2045-2322 (ISSN) 20452322 (eISSN)

Vol. 13 1 11288-

Ämneskategorier (SSIF 2011)

Annan medicinteknik

Annan materialteknik

Datavetenskap (datalogi)

DOI

10.1038/s41598-023-38466-2

PubMed

37438607

Mer information

Senast uppdaterat

2023-07-26