A practical guide to the implementation of artificial intelligence in orthopaedic research—Part 2: A technical introduction
Reviewartikel, 2024

Recent advances in artificial intelligence (AI) present a broad range of possibilities in medical research. However, orthopaedic researchers aiming to participate in research projects implementing AI-based techniques require a sound understanding of the technical fundamentals of this rapidly developing field. Initial sections of this technical primer provide an overview of the general and the more detailed taxonomy of AI methods. Researchers are presented with the technical basics of the most frequently performed machine learning (ML) tasks, such as classification, regression, clustering and dimensionality reduction. Additionally, the spectrum of supervision in ML including the domains of supervised, unsupervised, semisupervised and self-supervised learning will be explored. Recent advances in neural networks (NNs) and deep learning (DL) architectures have rendered them essential tools for the analysis of complex medical data, which warrants a rudimentary technical introduction to orthopaedic researchers. Furthermore, the capability of natural language processing (NLP) to interpret patterns in human language is discussed and may offer several potential applications in medical text classification, patient sentiment analysis and clinical decision support. The technical discussion concludes with the transformative potential of generative AI and large language models (LLMs) on AI research. Consequently, this second article of the series aims to equip orthopaedic researchers with the fundamental technical knowledge required to engage in interdisciplinary collaboration in AI-driven orthopaedic research. Level of Evidence: Level IV.

sports medicine

orthopaedics

machine learning

artificial intelligence

research methods

Författare

Bálint Zsidai

Sahlgrenska universitetssjukhuset

Göteborgs universitet

Janina Kaarre

Göteborgs universitet

University of Pittsburgh

Sahlgrenska universitetssjukhuset

Eric Narup

Sahlgrenska universitetssjukhuset

Göteborgs universitet

Eric Hamrin Senorski

Sahlgrenska universitetssjukhuset

Göteborgs universitet

Sportrehab

Ayoosh Pareek

Hospital for Special Surgery

Alberto Grassi

Göteborgs universitet

IRCCS Istituto Ortopedico Rizzoli, Bologna

Christophe Ley

Université du Luxembourg

Umile Giuseppe Longo

Università Campus Bio-Medico di Roma

Policlinico Universitario Campus Bio Medico

Elmar Herbst

Division of General Internal Medicine

Michael T. Hirschmann

Kantonsspital Baselland

Sebastian Kopf

Medizinische Hochschule Brandenburg Theodor Fontane

Romain Seil

Luxembourg Institute of Research in Orthopaedics

Centre Hospitalier de Luxembourg

Luxembourg Institute of Health

Thomas Tischer

Clinic for Orthopaedics and Trauma Surgery

Kristian Samuelsson

Göteborgs universitet

Sahlgrenska universitetssjukhuset

Robert Feldt

Chalmers, Data- och informationsteknik, Software Engineering

Journal of Experimental Orthopaedics

2197-1153 (eISSN)

Vol. 11 3 e12025

Ämneskategorier (SSIF 2011)

Språkteknologi (språkvetenskaplig databehandling)

Tvärvetenskapliga studier

DOI

10.1002/jeo2.12025

Mer information

Senast uppdaterat

2026-06-15