A different approach to enantioselective organic synthesis: absolute asymmetric synthesis of organometallic reagents.
Artikel i vetenskaplig tidskrift, 2009

Voilà, optical activity: Both enantiomers of 1-chloroindene have been synthesized in high selectivity from solely achiral starting materials, and without using optically active catalysts (see scheme). These symmetry-breaking syntheses provide a proof-of-concept for a new approach to asymmetric synthesis. NCS=N-chlorosuccinimide.

chemistry

chemical synthesis

Organometallic Compounds

Stereoisomerism

Indenes

chemical synthesis

Författare

Anders Lennartsson

Göteborgs universitet

Susanne Olsson

Göteborgs universitet

Jonas Sundberg

Göteborgs universitet

Mikael Håkansson

Göteborgs universitet

Angewandte Chemie - International Edition

1433-7851 (ISSN) 1521-3773 (eISSN)

Vol. 48 3137-40

Ämneskategorier

Kemi

DOI

10.1002/anie.200806222

PubMed

19322856