A different approach to enantioselective organic synthesis: absolute asymmetric synthesis of organometallic reagents.
Artikel i vetenskaplig tidskrift, 2009
Voilà, optical activity: Both enantiomers of 1-chloroindene have been synthesized in high selectivity from solely achiral starting materials, and without using optically active catalysts (see scheme). These symmetry-breaking syntheses provide a proof-of-concept for a new approach to asymmetric synthesis. NCS=N-chlorosuccinimide.
chemistry
chemical synthesis
Organometallic Compounds
Stereoisomerism
Indenes
chemical synthesis
Författare
Anders Lennartsson
Göteborgs universitet
Susanne Olsson
Göteborgs universitet
Jonas Sundberg
Göteborgs universitet
Mikael Håkansson
Göteborgs universitet
Angewandte Chemie - International Edition
1433-7851 (ISSN) 1521-3773 (eISSN)
Vol. 48 17 3137-40Ämneskategorier
Kemi
DOI
10.1002/anie.200806222
PubMed
19322856