Mikael Kubista

Showing 56 publications

2014

The workflow of single-cell expression profiling using quantitative real-time PCR

Anders Ståhlberg, Mikael Kubista
Expert Review of Molecular Diagnostics. Vol. 14 (3), p. 323-331
Journal article
2013

The added value of single-cell gene expression profiling

Anders Ståhlberg, V. Rusnakova, Mikael Kubista
Briefings in Functional Genomics. Vol. 12 (2), p. 81-89
Journal article
2013

Unrevealing biological secrets by single cell expression profiling

Mikael Kubista, Anders Ståhlberg
Drug Discovery World. Vol. Summer 2013
Review article
2013

Direct cell lysis for single-cell gene expression profiling.

David Svec, Daniel Andersson, Milos Pekny et al
Frontiers in Oncology. Vol. 3, p. 274-
Journal article
2011

High Troughput single cell expression profiling: taking a closer look on biological

Mikael Kubista, Linda Strömbom, David Svec et al
European Pharmaceutical Review. Vol. 16 (2), p. 20-24
Magazine article
2011

Defining cell populations with single-cell gene expression profiling: correlations and identification of astrocyte subpopulations.

Anders Ståhlberg, Daniel Andersson, Johan Aurelius et al
Nucleic Acids Research. Vol. 39 (4), p. e24-
Journal article
2011

DNA diagnostics gets digitised

Mikael Kubista, Anders Ståhlberg
Drug Discovery World (Fall), p. 77-82
Magazine article
2008

Protective role of reactive astrocytes in brain ischemia.

Lizhen Li, Andrea Lundkvist, Daniel Andersson et al
Journal of Cerebral Blood Flow and Metabolism. Vol. 28 (3), p. 468-81
Journal article
2007

Real-time immuno-PCR

Kristina Lind, Mikael Kubista
Real-time PCR, p. 205-210
Book chapter
2006

The real-time polymerase chain reaction

Mikael Kubista, JM Andrade, A Forootan et al
Mol Asp Med. Vol. 27, p. 95-125
Journal article
2006

Multiwavelength spectrophotometric determination of acidity constants of morin in methanol-water mixtures

A. Niazi, A. Yazdanipour, J. Ghasemi et al
Collection of Czechoslovak Chemical Communications. Vol. 71 (1), p. 1-14
Journal article
2006

Combining sequence-specific probes and DNA binding dyes in real-time PCR for specific nucleic acid quantification and melting curve analysis

Kristina Lind, Anders Ståhlberg, Neven Zoric et al
Biotechniques. Vol. 40 (3), p. 315-319
Journal article
2006

Spectrophotometric and thermodynamic study on the dimerization equilibrium of ionic dyes in water by chemometrics method

A Niazi, A Yazdanipour, J Ghasemi et al
Spectrochim Acta A Mol Biomol Spectrosc. Vol. 65 (1), p. 73-78
Journal article
2005

Neural cell adhesion molecule-deficient beta-cell tumorigenesis results in diminished extracellular matrix molecule expression and tumour cell-matrix adhesion

Joakim Håkansson, Xiaojie Xian, Liqun He et al
Tumor Biology. Vol. 26 (2), p. 103-112
Journal article
2005

Multiwavelength spectrophotometric determination of protolytic constants of 4-(2-pyridylazo)resorcinol (PAR) in binary dioxane + water mixtures

A. Rouhollahi, F. M. Kiaie, J. Ghasemi et al
Polish Journal of Chemistry. Vol. 79 (8), p. 1251-1263
Journal article
2005

Distribution of mRNA transcripts in the single pancreatic islet cell

M Bengtsson, Anders Ståhlberg, P Rorsman et al
Biophysical Journal. Vol. 1 (88), p. 569A-
Other conference contribution
2005

Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels

M Bengtsson, Anders Ståhlberg, P Rorsman et al
Genome Res. Vol. 15 (10), p. 1388-1392
Journal article
2005

Development and evaluation of three real-time immuno-PCR assemblages for quantification of PSA

Kristina Lind, Mikael Kubista
Journal of Immunological Methods. Vol. 304, p. 107-116
Journal article
2005

Thermodynamics study of the dimerization equilibria of rhodamine B and 6G in different ionic strengths by photometric titration and chemometrics method

Jahan Ghasemi, A Niazi, Mikael Kubista
Spectrochim Acta A Mol Biomol Spectrosc. Vol. 62 (1-3), p. 649-656
Journal article
2004

Comparison of reverse transcriptases in gene expression analysis.

Anders Ståhlberg, Mikael Kubista, Michael Pfaffl
Clinical Chemistry. Vol. 50 (9), p. 1678-80
Journal article
2003

Kinetic Outlier Detection (KOD) in real-time PCR.

Tzachi Bar, Anders Ståhlberg, Anders Muszta et al
Nucleic Acids Research. Vol. 31 (17), p. e105-
Journal article
2003

Quantitative real-time PCR method for detection of B-lymphocyte monoclonality by comparison of κ and λ immunoglobulin light chain expression

Anders Ståhlberg, Pierre Åman, Börje Ridell et al
Clinical Chemistry. Vol. 49 (1), p. 51-59
Journal article
2000

Detection of PCR products in real time using light-up probes.

Nicke Svanvik, Anders Ståhlberg, U Sehlstedt et al
Analytical Biochemistry. Vol. 287 (1), p. 179-82
Journal article
1994

PROPERTIES OF RECA COMPLEXES WITH HOMOPOLYMERIC DNA STRANDS DEPEND ON SEQUENCE COMPLEMENTARITY - IMPLICATIONS FOR THE MECHANISM OF STRAND EXCHANGE

Mikael Kubista, Bengt Nordén, M. Takahashi
Nucleosides and Nucleotides. Vol. 13 (1-3), p. 753-772
Journal article
1993

SEQUENCE DEPENDENCE OF 4',6-DIAMIDINO-2-PHENYLINDOLE (DAPI) DNA INTERACTIONS

Karl Jansen, Bengt Nordén, Mikael Kubista
Journal of the American Chemical Society. Vol. 115 (23), p. 10527-10530
Journal article
1993

Determination of Equilibrium-Constants by Chemometric Analysis of Spectroscopic Data

Mikael Kubista, Robert Sjöback, Bo Albinsson
Analytical Chemistry. Vol. 65 (8), p. 994-998
Journal article
1993

INTERACTION OF 4',6-DIAMIDINO-2-PHENYLINDOLE (DAPI) WITH POLY D(G-C)2 AND POLY D(G-M(5)C)2 - EVIDENCE FOR MAJOR GROOVE BINDING OF A DNA PROBE

Seog K. Kim, Svante Eriksson, Mikael Kubista et al
Journal of the American Chemical Society. Vol. 115 (9), p. 3441-3447
Journal article
1993

BINDING OF 4',6-DIAMIDINO-2-PHENYLINDOLE (DAPI) TO AT REGIONS OF DNA - EVIDENCE FOR AN ALLOSTERIC CONFORMATIONAL CHANGE

Svante Eriksson, Seog K. Kim, Mikael Kubista et al
Biochemistry. Vol. 32 (12), p. 2987-2998
Journal article
1992

RecA Protein-DNA Complexes Studied by Flow Linear Dichroism, Fluorescence and Small Angle Neutron Scattering

Bengt Nordén, Christer Elvingson, Per Hagmar et al
Structure and Function, Volume 2, p. 61-68
Book chapter
1992

STRUCTURE OF RECA DNA COMPLEXES STUDIED BY COMBINATION OF LINEAR DICHROISM AND SMALL-ANGLE NEUTRON-SCATTERING MEASUREMENTS ON FLOW-ORIENTED SAMPLES

Bengt Nordén, Christer Elvingson, Mikael Kubista et al
Journal of Molecular Biology. Vol. 226 (4), p. 1175-1191
Journal article
1992

LINEAR DICHROISM SPECTROSCOPY OF NUCLEIC-ACIDS

Bengt Nordén, Mikael Kubista, T. Kurucsev
Quarterly Reviews of Biophysics. Vol. 25 (1), p. 51-170
Journal article
1992

Quantitative Spectral Analysis Without Reference Samples

Mikael Kubista, Svante Eriksson, Bo Albinsson
Spectroscopy Europe. Vol. 4, p. 28-29
Journal article
1992

IONIC-STRENGTH DEPENDENCE OF THE BINDING OF METHYLENE-BLUE TO CHROMATIN AND CALF THYMUS DNA

Per Hagmar, Stefan Pierrou, P. Nielsen et al
Journal of Biomolecular Structure and Dynamics. Vol. 9 (4), p. 667-679
Journal article
1991

The Electronically Excited-States of 2-Phenylindole

Bo Albinsson, Svante Eriksson, Reidar Lyng et al
Chemical Physics. Vol. 151 (1), p. 149-157
Journal article
1991

COORDINATION OF MULTIPLE DNA-MOLECULES IN RECA FIBER EVIDENCED BY LINEAR DICHROISM SPECTROSCOPY

Masayuki Takahashi, Mikael Kubista, Bengt Nordén
Biochimie. Vol. 73 (2-3), p. 219-226
Journal article
1990

MULTISITE DISTRIBUTIONS OF SOLUTE MOLECULES IN MICELLES - BENZENE IN A NEMATIC PHASE OF POTASSIUM LAURATE DECANOL WATER

M. Chiesa, I. Domini, B. Samori et al
Gazzetta Chimica Italiana. Vol. 120 (11), p. 667-670
Journal article
1990

Electronic linear dichroism spectrum and transition moment directions of the hypermodified nucleic acid base Wye

Bo Albinsson, Mikael Kubista, Kjell Sandros et al
Journal of Physical Chemistry. Vol. 94 (10), p. 4006-4011
Journal article
1990

STRUCTURE OF A RECA-DNA COMPLEX FROM LINEAR DICHROISM AND SMALL-ANGLE NEUTRON-SCATTERING IN FLOW-ORIENTED SOLUTION

Bengt Nordén, Christer Elvingson, T. Eriksson et al
Journal of Molecular Biology. Vol. 216 (2), p. 223-228
Journal article
1990

REINTERPRETATION OF LINEAR DICHROISM OF CHROMATIN SUPPORTS A PERPENDICULAR LINKER ORIENTATION IN THE FOLDED STATE

Mikael Kubista, Per Hagmar, P. E. Nielsen et al
Journal of Biomolecular Structure and Dynamics. Vol. 8 (1), p. 37-54
Journal article
1990

STOICHIOMETRY, BASE ORIENTATION, AND NUCLEASE ACCESSIBILITY OF RECA DNA COMPLEXES SEEN BY POLARIZED-LIGHT IN FLOW-ORIENTED SOLUTION - IMPLICATIONS FOR THE MECHANISM OF GENETIC-RECOMBINATION

Mikael Kubista, Masayuki Takahashi, Bengt Nordén
Journal of Biological Chemistry. Vol. 265 (31), p. 18891-18897
Journal article
1989

Binding Stoichiometry and Structure of RecA-DNA Complexes Studied by Flow Linear Dichroism and Fluorescence Spectroscopy: Evidence for Multiple Heterogeneous-DNA Coordination

Masayuki Takahashi, Mikael Kubista, Bengt Nordén
Journal of Molecular Biology. Vol. 205 (1), p. 137-147
Journal article
1989

Characterization of the Electronic-Structure of 4',6-Diamidino-2-Phenylindole

Mikael Kubista, Björn Åkerman, Bo Albinsson
Journal of the American Chemical Society. Vol. 111 (18), p. 7031-7035
Journal article
1989

ELECTRIC AND FLOW LINEAR DICHROISM OF UNFOLDED AND CONDENSED CHROMATIN - A COMPARATIVE-STUDY AT LOW AND INTERMEDIATE IONIC-STRENGTH

Per Hagmar, R. Marquet, P. Colson et al
Journal of Biomolecular Structure and Dynamics. Vol. 7 (1), p. 19-33
Journal article
1989

NEAR-ULTRAVIOLET ELECTRONIC-TRANSITIONS OF THE TRYPTOPHAN CHROMOPHORE - LINEAR DICHROISM, FLUORESCENCE ANISOTROPY, AND MAGNETIC CIRCULAR-DICHROISM SPECTRA OF SOME INDOLE-DERIVATIVES

Bo Albinsson, Mikael Kubista, Bengt Nordén et al
Journal of Physical Chemistry. Vol. 93 (18), p. 6646-6654
Journal article
1989

BINDING OF RECA PROTEIN TO Z-FORM DNA STUDIED WITH CIRCULAR AND LINEAR DICHROISM SPECTROSCOPY

M. Takahashi, Mikael Kubista, Bengt Nordén
Journal of Biological Chemistry. Vol. 264 (15), p. 8568-8574
Journal article
1988

Flow linear dichroism supports an accordion model for the salt-induced condensation of chromatin

Mikael Kubista, P. Nielsen, Bengt Nordén
Biochemical Pharmacology. Vol. 37 (9), p. 1813-1814
Journal article
1988

Induced circular dichroism in nonintercalative DNA-drug complexes: sector rules for structural applications

Mikael Kubista, Björn Åkerman, Bengt Nordén
Journal of Physical Chemistry. Vol. 92 (8), p. 2352-2356
Journal article
1988

Competitive Binding Between Unmodified and Etheno DNA Provides Information About Structure and Stoichiometry of RECA-DNA Complexes

Mikael Kubista, M. Takahashi, Bengt Nordén
Nucleosides and Nucleotides. Vol. 7 (5-6), p. 783-786
Journal article
1988

Characterization of the Spectroscopic Properties of Aromatic-Molecules by Polarized Spectroscopy

Mikael Kubista, Bo Albinsson, Björn Åkerman et al
Finnish Chemical Letters. Vol. 15 (3-4), p. 38-39
Journal article
1988

Linear Dichroism and Induced Circular Dichroism for Studying Structure and Interactions of DNA

Bengt Nordén, Mikael Kubista
Polarized spectroscopy of ordered systems / edited by B. Samori' and E.W. Thulstrup; (Proceedings of the NATO Advanced Study Institute on New Developments in Polarized Spectroscopy of Ordered Systems, Rimini, Italy, October 11-23, 1987), p. 133-165
Other conference contribution
1987

Linear Dichroism - A Potential Method for Studying DNA-Protein Interaction.

Mikael Kubista, Masayuki Takahashi, Bengt Nordén
Structure, dynamics, and function of biomolecules; European Biophysical Societies Association.Workshop (1 :Saltsjöbaden :1986), p. 145-147
Other conference contribution
1987

Characterization of interaction between DNA and 4',6-diamidino-2-phenylindole by optical spectroscopy

Mikael Kubista, Björn Åkerman, Bengt Nordén
Biochemistry. Vol. 26 (14), p. 4545-4553
Journal article
1987

Linear dichroism study of RecA-DNA complexes. Structural evidence and binding stoichiometries

M. Takahashi, Mikael Kubista, Bengt Nordén
Journal of Biological Chemistry. Vol. 262 (17), p. 8109-8111
Journal article
1985

Structural transitions of chromatin at low salt concentrations: a flow linear dichroism study

Mikael Kubista, Torleif Härd, P. E. Nielsen et al
Biochemistry. Vol. 24 (23), p. 6336-6342
Journal article

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