Mingtao Huang

Showing 17 publications

2022

Improving recombinant protein production by yeast through genome-scale modeling using proteome constraints

Feiran Li, Yu Chen, Qi Qi et al
Nature Communications. Vol. 13 (1)
Journal article
2019

RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae

Guokun Wang, Sara M. Björk, Mingtao Huang et al
Proceedings of the National Academy of Sciences of the United States of America. Vol. 116 (19), p. 9324-9332
Journal article
2018

Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative

Zongijie Dai, Mingtao Huang, Yun Chen et al
Nature Communications. Vol. 9 (1)
Journal article
2018

Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast

Jichen Bao, Mingtao Huang, Dina Petranovic Nielsen et al
AMB Express. Vol. 8 (1)
Journal article
2018

Engineering the protein secretory pathway of Saccharomyces cerevisiae enables improved protein production

Mingtao Huang, Guokun Wang, Jiufu Qin et al
Proceedings of the National Academy of Sciences of the United States of America. Vol. 115 (47), p. E11025-E11032
Journal article
2018

High-throughput microfluidics for the screening of yeast libraries

Mingtao Huang, H. N. Joensson, Jens B Nielsen
Methods in Molecular Biology, p. 307-317
Book chapter
2018

Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis

Tao Yu, Yongjin Zhou, Mingtao Huang et al
Cell. Vol. 174 (6), p. 1549-1572
Journal article
2017

Efficient protein production by yeast requires global tuning of metabolism

Mingtao Huang, Jichen Bao, B. M. Hallstrom et al
Nature Communications. Vol. 8 (1)
Journal article
2017

Moderate Expression of SEC16 Increases Protein Secretion by Saccharomyces cerevisiae

Jichen Bao, Mingtao Huang, Dina Petranovic Nielsen et al
Applied and Environmental Microbiology. Vol. 83 (14), p. Article no. UNSP e03400-16
Journal article
2017

Exploring the potential of Saccharomyces cerevisiae for biopharmaceutical protein production

Guokun Wang, Mingtao Huang, Jens B Nielsen
Current Opinion in Biotechnology. Vol. 48, p. 77-84
Review article
2016

Characterization of physiological and transcriptional properties of improved protein secretion yeast strains

Mingtao Huang, Jichen Bao, B. M. Hallstrom et al
Metabolic Engineering, p. 639-640
Paper in proceeding
2015

Micro-droplet based directed evolution outperforms conventional laboratory evolution

S. L. Sjostrom, Mingtao Huang, Jens B Nielsen et al
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014; United States; 26-30 October 2014, p. 169-171
Paper in proceeding
2015

Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine

J. Qin, Yongjin Zhou, Anastasia Krivoruchko et al
Nature Communications. Vol. 6 (Sept.), p. Art. no. 8224-
Journal article
2015

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast

Mingtao Huang, Y. Bai, S. L. Sjostrom et al
Proceedings of the National Academy of Sciences of the United States of America. Vol. 112 (34), p. E4689-E4696
Journal article
2014

High-throughput screening for industrial enzyme production hosts by droplet microfluidics

S. L. Sjostrom, Y. Bai, Mingtao Huang et al
Lab on a Chip - Miniaturisation for Chemistry and Biology. Vol. 14 (4), p. 806-813
Journal article
2014

Improved Production of a Heterologous Amylase in Saccharomyces cerevisiae by Inverse Metabolic Engineering

Zihe Liu, Lifang Liu, Tobias Österlund et al
Applied and Environmental Microbiology. Vol. 80 (17), p. 5542-5550
Journal article
2013

Droplet based directed evolution of yeast cell factories doubles production of industrial enzymes

S. L. Sjostrom, Y. Bai, Mingtao Huang et al
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013, p. 1270-1272
Paper in proceeding

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Showing 1 research projects

2012–2017

Engineering the Secretory Pathway for Recombinant Protein Secretion in Saccharomyces cerevisiae

Mingtao Huang Systems and Synthetic Biology
Jens B Nielsen Systems and Synthetic Biology
Dina Petranovic Nielsen Systems and Synthetic Biology
Novo Nordisk Foundation
Knut and Alice Wallenberg Foundation
Chalmers

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