FunAromatics - High throughput technologies för production of aromatic biochemicals with fungi

Research Project, 2022 – 2027

In this project, the focus is on constructing microbes, yeasts and filamentous fungi (molds) that are used for biotechnological production of aromatic biochemicals. These chemicals are used in the manufacture of various medicines or as additives in cosmetics or food. Today, most aromatic chemicals are produced from oil, through polluting chemical reactions. Thus, the need for new, sustainable production methods is urgent. The production of biochemicals will be improved through new cutting-edge technology, using genetic scissors and biosensors, genetic tools that can measure the content of chemicals produced by the cells. The biosensors developed will serve as tools to determine what genetic engineering can be done to increase the production and to evaluate strain performance. Strains will be constructed and characterized in high-throughput to ensure success and increase knowledge. More productive microbial cell factories are needed for bio-based chemicals to be competitive and applied industrially.