Probing DNA conductivity with photoinduced electron transfer and scanning tunneling microscopy
Paper in proceedings, 2000

The possibility that the stacked DNA bases can mediate vectorial electron transfer has been examined using two different approaches. Experiments on photoinduced electron transfer with intercalated donors and accepters (either randomly bound or linked dyads of ruthenium complex and viologen) indicate that while DNA may be a better medium than acetonitrile for electron transfer over short distances (2-3-base pair, equivalent to 10-14 Angstrom centre-to-centre separation), it is a poor medium for transport over larger separations. Attempts to measure conductivity of individual DNA molecules using scanning tunneling microscopy to image mixed monolayers of mercaptohexanol (MCH) and 30-mer or 10-mer DNAs with alkanethiol linkers also indicate that DNA in its native state is a poor conductor. AFM images of the DNA/MCH mixed monolayers show that the DNA molecules extend vertically upward from the surface in such surface architectures.

Author

Eimer Tuite

Department of Physical Chemistry

Per Lincoln

Department of Physical Chemistry

Johan Olofsson

Department of Physical Chemistry

Hans-Christian Becker

Department of Physical Chemistry

Björn Önfelt

Department of Physical Chemistry

D. Erts

Bengt Nordén

Department of Physical Chemistry

Journal of Biomolecular Structure and Dynamics

0739-1102 (ISSN)

277-283

Subject Categories

Physical Chemistry

Biochemistry and Molecular Biology

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Created

10/6/2017