Probing DNA conductivity with photoinduced electron transfer and scanning tunneling microscopy
Paper i proceeding, 2000

The possibility that the stacked DNA bases can mediate vectorial electron transfer has been examined using two different approaches. Experiments on photoinduced electron transfer with intercalated donors and accepters (either randomly bound or linked dyads of ruthenium complex and viologen) indicate that while DNA may be a better medium than acetonitrile for electron transfer over short distances (2-3-base pair, equivalent to 10-14 Angstrom centre-to-centre separation), it is a poor medium for transport over larger separations. Attempts to measure conductivity of individual DNA molecules using scanning tunneling microscopy to image mixed monolayers of mercaptohexanol (MCH) and 30-mer or 10-mer DNAs with alkanethiol linkers also indicate that DNA in its native state is a poor conductor. AFM images of the DNA/MCH mixed monolayers show that the DNA molecules extend vertically upward from the surface in such surface architectures.

Författare

Eimer Tuite

Institutionen för fysikalisk kemi

Per Lincoln

Institutionen för fysikalisk kemi

Johan Olofsson

Institutionen för fysikalisk kemi

Hans-Christian Becker

Institutionen för fysikalisk kemi

Björn Önfelt

Institutionen för fysikalisk kemi

D. Erts

Bengt Nordén

Institutionen för fysikalisk kemi

Journal of Biomolecular Structure and Dynamics

0739-1102 (ISSN)

277-283

Ämneskategorier

Fysikalisk kemi

Biokemi och molekylärbiologi

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Skapat

2017-10-06