Per Lincoln

2022

Left versus right: Exploring the effects of chiral threading intercalators using optical tweezers

Another step toward understanding the binding mode of other derivatives of [Ru(phen)(2)L] complexes

Effect of Chirality on the Elastic Properties of the DNA-Threading Binuclear Ruthenium Complex

Another step toward understanding the binding mode of other derivatives of [Ru(phen)<inf>2</inf>L] complexes

2019

Canonical DNA minor groove insertion of bisbenzamidine-Ru(ii) complexes with chiral selectivity

2019

Diastereomeric Crowding Effects in the Competitive DNA Intercalation of Ru(phenanthroline)2dipyridophenazine2+ Enantiomers

2019

Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects

2018

Effects of methyl substitution on DNA binding enthalpies of enantiopure Ru(phenanthroline)2dipyridophenazine2+ complexes

2018

Competitive DNA binding of Ru(bpy)2dppz2+ enantiomers studied with isothermal titration calorimetry (ITC) using a direct and general binding isotherm algorithm

Reshaping the Energy Landscape Transforms the Mechanism and Binding Kinetics of DNA Threading Intercalation

2017

Guanine Can Direct Binding Specificity of Ru–dipyridophenazine (dppz) Complexes to DNA through Steric Effects

Dissecting the Dynamic Pathways of Stereoselective DNA Threading Intercalation

Role of the Moiety Chirality in Determining the DNA Binding Characteristics of Threading Intercalators

Significance of Steric Bulk in DNA Threading Intercalation Revelaed through Force-Dependent Kinetics

2016

DNA intercalation optimized by two-step molecular lock mechanism

2016

Diastereomeric bactericidal effect of Ru(phenanthroline)(2)dipyridophenazine

2015

A ruthenium dimer complex with a flexible linker slowly threads between DNA bases in two distinct steps

Resolving the DNA Binding Mode of a Rotationally Flexible Binuclear Ruthenium Complex

The Role of the Threading Moiety in DNA Threading Intercalation by Ruthenium Dimer Complexes

2015

Binding of Ru(terpyridine)(pyridine)dipyridophenazine to DNA studied with polarized spectroscopy and calorimetry

2014

DNA-Binding Properties of Amidine-Substituted Spiropyran Photoswitches

2014

Strong DNA deformation required for extremely slow DNA threading intercalation by a binuclear ruthenium complex

Thread Insertion of a Bis(dipyridophenazine) Diruthenium Complex into the DNA Double Helix by the Extrusion of AT Base Pairs and Cross-Linking of DNA Duplexes

Enhanced Cellular Uptake of Antisecretory Peptide AF-16 through Proteoglycan Binding

Kinetics of DNA Threading Intercalation by a Rigid Ruthenium Complex Dimer

Lifetime Heterogeneity of DNA-Bound dppz Complexes Originates from Distinct Intercalation Geometries Determined by Complex-Complex Interactions

Sensitivity of Ru(phen)(2)dppz (2+) light switch emission to ionic strength, temperature, and DNA sequence and conformation

Comprehensive Study on the Binding of Iron Schiff Base Complex with DNA and Determining the Binding Mode

Linguistic Resources Used in Grade 8 Students’ Submicro Level Explanations-Science Items from TIMSS 2007

Minor-Groove Binding Drugs: Where Is the Second Hoechst 33258 Molecule?

Rate of hydrolysis in ATP synthase is fine-tuned by alpha-subunit motif controlling active site conformation

2013

Initial DNA Interactions of the Binuclear Threading Intercalator Λ,Λ-[μ-bidppz(bipy)4Ru2]4+: An NMR Study with [d(CGCGAATTCGCG)]2

Bridging Ligand Length Controls AT Selectivity and Enantioselectivity of Binuclear Ruthenium Threading Intercalators

2013

Enantioselective Cyclization of Photochromic Dithienylethenes Bound to DNA

2013

Interactions of Binuclear Ruthenium(II) Complexes with Oligonucleotides in Hydrogel Matrix: Enantioselective Threading Intercalation into GC Context

DNA Sequence and Ancillary Ligand Modulate the Biexponential Emission Decay of Intercalated [Ru(L)2dppz]2+ Enantiomers

Cell surface binding and uptake of arginine- and lysine-rich penetratin peptides in absence and presence of proteoglycans

Spectroscopic study on the interaction of ct-DNA with manganese Salen complex containing triphenyl phosphonium groups

2012

Effects of chirality on the intracellular localization of binuclear ruthenium(II) polypyridyl complexes

Towards Artificial Photosynthesis of CO2-Neutral Fuel: Homogenous Catalysis of CO2-Selective Reduction to Methanol Initiated by Visible-Light-Driven Multi-Electron Collector

Transition State of Rare Event Base Pair Opening Probed by Threading into Looped DNA

Tryptophan Orientations in Membrane-Bound Gramicidin and Melittin - a Comparative Linear Dichroism Study on Transmembrane and Surface-Bound Peptides

Stereoselectivity for DNA Threading Intercalation of Short Binuclear Ruthenium Complexes

Ruthenium(II) Complex Enantiomers as Cellular Probes for Diastereomeric Interactions in Confocal and Fluorescence Lifetime Imaging Microscopy

Using Ethidium To Probe Nonequilibrium States of DNA Condensed for Gene Delivery

Binding of cell-penetrating penetratin peptides to plasma membrane vesicles correlates directly with cellular uptake

2011

Sequential One-Pot Ruthenium-Catalyzed Azide-Alkyne Cycloaddition from Primary Alkyl Halides and Sodium Azide

Double-lock ratchet mechanism revealing the role of alpha SER-344 in FoF1 ATP synthase

2011

Bis 4,5-diazafluoren-9-one silver(I) nitrate: synthesis, X-ray structures, solution chemistry, hydrogel loading, DNA coupling and anti-bacterial screening

Characterizing the language of Swedish students' written explanations to TIMSS 2007 science items

Environmental effects on the photophysics of transition metal complexes with dipyrido 2,3-a:3 ',2 '-c phenazine (dppz) and related ligands

2011

Nanofabrication Yields. Hybridization and Click-Fixation of Polycyclic DNA Nanoassemblies

Slow Threading Intercalation of Monomeric Ru(II) Complexes with 10,13-Diarylsubstituted dppz Ligands

Correlation Between Cellular Localization and Binding Preference to RNA, DNA, and Phospholipid Membrane for Luminescent Ruthenium(II) Complexes

Lipophilic ruthenium complexes with tuned cell membrane affinity and photoactivated uptake

AT-Specific DNA Binding of Binuclear Ruthenium Complexes at the Border of Threading Intercalation

Mechanical Control of ATP Synthase Function: Activation Energy Difference between Tight and Loose Binding Sites

Effects of PEGylation and acetylation of PAMAM dendrimers on DNA binding, cytotoxicity and in vitro transfection efficiency

Self-Assembly of Functionalizable Two-Component 3D DNA Arrays through the Induced Formation of DNA Three-Way-Junction Branch Points by Supramolecular Cylinders

2010

Molecular AND-logic for dually controlled activation of a DNA-binding spiropyran

Synthesis and DNA threading properties of quaternary ammonium Ru(phen)(2)(dppz) (2+) derivatives

Thermodynamic Aspects of DNA Nanoconstruct Stability and Design

Effect of bridging ligand structure on the thermal stability and DNA binding properties of iron(II) triple helicates

Assigning Membrane Binding Geometry of Cytochrome c by Polarized Light Spectroscopy

Supercoil-Accelerated DNA Threading Intercalation

Complex DNA binding kinetics resolved-by combined circular dichroism and luminescence analysis

A three-dimensional net of Δ-tris(1,10-phenanthroline)ruthenium(II) in the dual-metal self-assembly of bis[tris(1,10-phenanthroline)ruthenium(II)] tetraisothiocyanatoiron(II) bis(perchlorate)

DNA condensation by PAMAM dendrimers: Self-assembly characteristics and effect on transcription

2008

Photoswitched DNA-binding of a photochromic spiropyran

DNA Polymorphism as an Origin of Adenine-Thymine Tract Length-Dependent Threading Intercalation Rate

Finding at-DNA--kinetic recognition of long adenine-thymine stretches by metal-ligand complexes.

Addressable molecular node assembly - high information density DNA nanostructures

Ligand-specific temperature-dependent shifts in EC50 values for the GABA(A) receptor

Mechanically manipulating the DNA threading intercalation rate

Conformational flexibility in DNA nanoconstructs: A time-resolved fluorescence resonance energy transfer study

Luminescent Dipyridophenazine-Ruthenium Probes for Liposome Membranes

Binding geometry and photophysical properties of DNA-threading binuclear ruthenium complexes

Tryptophan Orientation in Model Lipid Membranes

Template-directed oligonucleotide strand ligation, covalent intramolecular DNA circularization and catenation using click chemistry

2007

Addressable high-information-density DNA nanostructures

Counterion-mediated Membrane Penetration: Cationic Cell-penetrating Peptides overcome Born Energy Barrier by Ion-pairing with Phospholipids

Membrane binding of pH-sensitive influenza fusion peptides. Positioning, configuration, and induced leakage in a lipid vesicle model

Retinoid chromophores as probes of membrane lipid order

AT-dependent luminescence of DNA-threading ruthenium complexes

Kinetic characterization of an extremely slow DNA binding equilibrium

2007

Synthesis and Oligonucleotide Incorporation of Fluorescent Cytosine Analogue tC: a Promising Nucleic Acid Probe

2007

Triplex addressability as a basis for functional DNA nanostructures

Kinetic recognition of AT-rich DNA by ruthenium complexes

Controlling desensitized states in ligand-receptor interaction studies with cyclic scanning patch-clamp Protocols

Comparing mono- and divalent DNA groove binding cyanine dyes--Binding geometries, dissociation rates, and fluorescence properties

Sequence-specific DNA Binding Agents

A biohybrid dynamic random access memory

Membrane interactions of cell-penetrating peptides probed by tryptophan fluorescence and dichroism techniques: Correlations of structure to cellular uptake

A polarized-light spectroscopy study of interactions of a hairpin polyamide with DNA

Monitoring the DNA binding kinetics of a binuclear ruthenium complex by energy transfer: Evidence for slow shuffling

Enantioselective luminescence quenching of DNA light-switch [Ru(phen) 2dppz]2+ by electron transfer to structural homologue [Ru(phendione)2dppz]2+

Mechanism of DNA Threading Intercalation of Binuclear Ru Complexes: Uni- or Bimolecular Pathways Depending on Ligand Structure and Binding Density

2005

Fluorescent Properties of DNA Base Analogue tC upon Incorporation into DNA - Negligible Influence of Neighboring Bases on Fluorescence Quantum Yield

Membrane destabilizing properties of cell-penetrating peptides

Membrane binding and translocation of cell-penetrating peptides

Vesicle size-dependent translocation of penetratin analogs across lipid membranes

Vesicle membrane interactions of penetratin analogs

Ambivalent Intercalators for DNA: L-Shaped Platinum(II) Complexes

2004

DNA adopts normal B-form upon incorporation of highly fluorescent DNA base analogue tC: NMR structure and UV-Vis spectroscopy characterization

Effects of methyl substitution on radiative and solvent quenching rate constants of [Ru(phen)(2)dppz](2+) in polyol solvents and bound to DNA

Simultaneous binding of Ruthenium(II) [(1,10-phenanthroline)2(dipyridophenazine}]2+ and Minor Groove Binder 4,6-Diamidino-2-phenylindole to poly[d(A-T) 2] at high binding Densities: Observation of Fluorescence Resonance Energy Transfer Across the DNA Stem

Application of a Novel Analysis To Measure the Binding of the Membrane-Translocating Peptide Penetratin to Negatively Charged Liposomes

Picosecond and Steady-State Emission of [Ru(dppz)(phen)2]2+ in Glycerol: Anomalous Temperature Dependence Reveals Fast Excited State Equilibrium

2003

Meso stereoisomer as a probe of enantioselective threading intercalation of semirigid ruthenium complex [µ-(11,11'-bidppz)(phen)4Ru2]4+

2003

Photophysical Characterization of Fluorescent DNA Base Analogue, tC

2003

Micelle-sequestered dissociation of cationic DNA-intercalated drugs: Unexpected surfactant-induced rate enhancement

Orientation and conformation of cell-penetrating peptide penetratin in phospholipid vesicle membranes determined by polarized-light spectroscopy.

Cell Studies of the DNA Bis-Intercalator Delta-Delta [mu-C4(cpdppz)2(phen)4Ru2dppz]4+: Toxic Effects and Properties as a Light- Emitting DNA Probe in V79 Chinese Hamster Cells

Absolute configuration and electronic state properties of light-switch complex [Ru(phen)2dppz]2+ deduced from oriented circular dichroism in a lamellar liquid crystal host

2002

DNA-binding of semirigid binuclear ruthenium complex Δ,Δ-[µ-(11,11 '-bidppz)(phen)4Ru2]4+: Extremely slow intercalation kinetics

Picosecond Kerr-Gated Time-Resolved Raman Spectroscopy of the [Ru(phen)2dppz]2+ Chromophore Interacting with DNA

Formation of DNA Triple Helices by an Oligonucleotide Conjugated to a Fluorescent Ruthenium Complex

Invisible Liposomes: Refractive Index Matching with Sucrose Enables Flow Dichroism Assessment of Peptide Orientation in Lipid Vesicle Membranes

Enantioselective DNA Threading Dynamics by Phenazine-Linked [Ru(phen)2dppz]2+ Dimers

A highly fluorescent DNA base analogue that forms Watson-Crick base pairs with guanine

2001

A simple model for gene targeting

Picosecond Time-Resolved Resonance Raman Probing the Light Switch States of [Ru(Phen)2dppz]2+

Ligand Substituents of Ruthenium Dipyridophenazine Complexes Sensitively Determine Orientation in Liposome Membrane

Influence of DNA on Charge Separation Processes of Ruthenium(II) Complexes

Probing DNA conductivity with photoinduced electron transfer and scanning tunneling microscopy

Femtosecond linear dichroism of DNA-intercalating chromophores: Solvation and charge separation dynamics of [Ru(phen)2dppz]2+ systems

Interactions of tris(phenanthroline)ruthenium(II) enantiomers with DNA: Effects on helix flexibility studied by the electrophoretic behavior of reptating DNA in agarose gel

A molecular staple for DNA: Threading bisintercalating D-[Ru(phen)2DPPZ]2+ dimer

DNA binding of L- and D-cis-b-[-[Ru(RR-picchxn)(phen)]2+studied by NMR and flow linear dichroism spectroscopy

DNA Interactions with Chiral Polyaza-aromatic Ruthenium(II) Complexes

DNA Binding Geometries of Ruthenium(II) Complexes with 1,10-Phenanthroline and 2,2'-Bipyridine Ligands Studied with Linear Dichroism Spectroscopy. Borderline Cases of Intercalation

Recognition and characterization of binding modes of Δ- and Λ-[Ru(phen)3]2+ and Δ- and Λ-[Ru(phen)2DPPZ]2+ by the 23Na NMR Relaxation and Binding Free Energy Parameters

Photophysical evidence that Delta- and Lambda-[Ru(phen)2(dppz)]2+ intercalate DNA from the minor groove

Short-circuiting the molecular wire: Cooperative binding of Delta- [Ru(phen)2dppz]2+ and Delta-[Rh(phi)2bipy]3+ to DNA

Binding Mode of [Ruthenium(II) (1,10-Phenanthroline)2L]2+ with Poly(dT*dA-dT) Triplex. Ligand Size Effect on Third-Strand Stabilization

Absence of chiral discrimination in the interaction of tris(diphenanthroline)ruthenium(II) with DNA

Binuclear ruthenium(II) phenanthroline compounds with extreme binding affinity for DNA

DNA Interactions with Substitution-Inert Transition Metal Ion Complexes

Diastereomeric DNA-binding geometries of intercalated ruthenium(II) trischelates probed by linear dichroism: [Ru(phen)2DPPZ]2+ and [Ru(phen)2BDPPZ]2+

Interaction of Delta- and Lambda-[Ru(phen)2DPPZ]2+ with DNA: A Calorimetric and Equilibrium Binding Study

BINDING OF DAPI ANALOG 2,5-BIS(4-AMIDINOPHENYL)FURAN TO DNA

DNA-BINDING OF DELTA- RU(PHEN)2DPPZ 2+ AND LAMBDA- RU(PHEN)2DPPZ 2+

CONFORMATION OF THIOCOLCHICINE AND 2 B-RING-MODIFIED ANALOGS BOUND TO TUBULIN STUDIED WITH OPTICAL SPECTROSCOPY