Molecular AND-logic for dually controlled activation of a DNA-binding spiropyran
Artikel i vetenskaplig tidskrift, 2010

A spiropyran photoswitch is activated using UV light and protons from a form that shows no interaction with DNA to a form that binds to DNA by intercalation. This scheme is interpreted as a biologically relevant logic AND gate with potential applications as a dually controlled anticancer drug.

light-activation

DNA recognition

DNA-binding

photochromism

molecular logic

Författare

Martin Hammarson

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

Johanna Andersson

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

Shiming Li

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

Per Lincoln

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

Joakim Andreasson

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

Chemical Communications

1359-7345 (ISSN)

Vol. 46 7130-7132

Ämneskategorier

Fysikalisk kemi

DOI

10.1039/c0cc01682a