Magnetic resonance analysis of capillary formation reaction front dynamics in alginate gels
Journal article, 2011
The formation of heterogeneous structures in biopolymer gels is of current interest for biomedical applications and is of fundamental interest to understanding the molecular level origins of structures generated from disordered solutions by reactions. The cation-mediated physical gelation of alginate by calcium and copper is analyzed using magnetic resonance measurements of spatially resolved molecular dynamics during gel front propagation. Relaxation time and pulse-field gradient methods are applied to determine the impact of ion front motion on molecular translational dynamics. The formation of capillaries in alginate copper gels is correlated to changes in translational dynamics.
calcium cations
glassy-polymers
capillary
transition
pulsed-field gradient
NMR
alginate
formation
diffusion
relaxation
relaxation
gelation
MRI
magnetic resonance
scaffolds
gelation
imaging mri
microscopy
heavy-metal uptake
dissipative dynamics
Author
J. E. Maneval
Bucknell University
Diana Bernin
Chalmers, Chemical and Biological Engineering, Applied Surface Chemistry
SuMo Biomaterials
H. T. Fabich
Montana State University
J. D. Seymour
Montana State University
S. L. Codd
Montana State University
Magnetic Resonance in Chemistry
0749-1581 (ISSN) 1097-458X (eISSN)
Vol. 49 10 627-640Subject Categories
Chemical Sciences
DOI
10.1002/mrc.2788