Highlights of selected recent electrochemical measurements in living systems
Journal article, 2012
Since the early work carried out by Ralph Adams in the 1970s, electrochemistry has been established as a powerful analytical tool for neuroscience. In this review, we focus on some novel and innovative methods for the electrochemical analysis of biological samples reported during the last five years. Recent findings in the neurochemistry of Drosophila melanogaster, a new and simple animal model, are summarized. A wealth of technical improvements of the electrode materials or of the instrumentation has been used to achieve higher sensitivity or robustness, to detect new biologically relevant analytes or simply to offer new experimental possibilities. Electrochemical imaging of exocytosis, in vivo or in vitro at the single cell level, is also summarized here. Finally, new perspectives and emerging technologies are discussed.
scan cyclic voltammetry
In vivo sensing
diamond
electroanalytical techniques
Electrochemical imaging
microelectrodes
freeze-fracture
Bioanalysis
carbon-fiber
Drosophila melanogaster
intense
individual chromaffin cells
release
Neurochemistry
hydrogen-peroxide
transmitter release
frog neuromuscular-junctions
microelectrodes
Author
R. Trouillon
University of Gothenburg
M. I. Svensson
University of Gothenburg
E. C. Berglund
University of Gothenburg
Ann-Sofie Cans
Chalmers, Chemical and Biological Engineering, Analytical Chemistry
Andrew Ewing
Chalmers, Chemical and Biological Engineering, Analytical Chemistry
Electrochimica Acta
0013-4686 (ISSN)
Vol. 84 84-95Subject Categories
Inorganic Chemistry
DOI
10.1016/j.electacta.2012.04.164