Highlights of selected recent electrochemical measurements in living systems
Artikel i vetenskaplig tidskrift, 2012

Since the early work carried out by Ralph Adams in the 1970s, electrochemistry has been established as a powerful analytical tool for neuroscience. In this review, we focus on some novel and innovative methods for the electrochemical analysis of biological samples reported during the last five years. Recent findings in the neurochemistry of Drosophila melanogaster, a new and simple animal model, are summarized. A wealth of technical improvements of the electrode materials or of the instrumentation has been used to achieve higher sensitivity or robustness, to detect new biologically relevant analytes or simply to offer new experimental possibilities. Electrochemical imaging of exocytosis, in vivo or in vitro at the single cell level, is also summarized here. Finally, new perspectives and emerging technologies are discussed.

scan cyclic voltammetry

In vivo sensing

diamond

electroanalytical techniques

Electrochemical imaging

microelectrodes

freeze-fracture

Bioanalysis

carbon-fiber

Drosophila melanogaster

intense

individual chromaffin cells

release

Neurochemistry

hydrogen-peroxide

transmitter release

frog neuromuscular-junctions

microelectrodes

Författare

R. Trouillon

Göteborgs universitet

M. I. Svensson

Göteborgs universitet

E. C. Berglund

Göteborgs universitet

Ann-Sofie Cans

Chalmers, Kemi- och bioteknik, Analytisk kemi

Andrew Ewing

Chalmers, Kemi- och bioteknik, Analytisk kemi

Electrochimica Acta

0013-4686 (ISSN)

Vol. 84 84-95

Ämneskategorier

Oorganisk kemi

DOI

10.1016/j.electacta.2012.04.164