BacMet: antibacterial biocide and metal resistance genes database
Journal article, 2014

Antibiotic resistance has become a major human health concern due to widespread use, misuse and overuse of antibiotics. In addition to antibiotics, antibacterial biocides and metals can contribute to the development and maintenance of antibiotic resistance in bacterial communities through co-selection. Information on metal and biocide resistance genes, including their sequences and molecular functions, is, however, scattered. Here, we introduce BacMet (http://bacmet.biomedicine.gu.se)-a manually curated database of antibacterial biocide-and metal-resistance genes based on an in-depth review of the scientific literature. The BacMet database contains 470 experimentally verified resistance genes. In addition, the database also contains 25 477 potential resistance genes collected from public sequence repositories. All resistance genes in the BacMet database have been organized according to their molecular function and induced resistance phenotype.

Author

C. Pal

University of Gothenburg

Johan Bengtsson-Palme

University of Gothenburg

Christopher Rensing

University of Copenhagen

Erik Kristiansson

University of Gothenburg

Chalmers, Mathematical Sciences, Mathematical Statistics

D. G. Joakim Larsson

University of Gothenburg

Nucleic Acids Research

0305-1048 (ISSN) 1362-4962 (eISSN)

Vol. 42 D1 D737-D743

Subject Categories

Biological Sciences

Bioinformatics (Computational Biology)

DOI

10.1093/nar/gkt1252

More information

Latest update

5/8/2018 1