Approaches to study yeast cell aging and death
Journal article, 2014
For millennia, yeast has been exploited to obtain fermentation products, such as foods and beverages. For c. 50years, yeast has been an established model organism for basic and applied research, and more specifically, for c. 15years, this unicellular organism has been applied to dissect molecular mechanisms of cell aging and programmed cell death. In this review, we present an overview of approaches to study cell aging and death in yeast, including lifespan assessments, calorie restriction, cell viability, survival, and death markers.
span
CHRONOLOGICAL LIFE-SPAN
CALORIE RESTRICTION
replicative life
ALPHA-SYNUCLEIN
STATIONARY-PHASE
CHROMOSOMAL REARRANGEMENTS
SYSTEMS BIOLOGY
chronological life span
PROTEIN-KINASE
MITOCHONDRIAL FISSION
SACCHAROMYCES-CEREVISIAE
yeast survival
Saccharomyces cerevisiae
yeast cell death
MODEL SYSTEM
oxidative stress
Author
M. G. Mirisola
University of Palermo
R. J. Braun
University of Bayreuth
Dina Petranovic Nielsen
Chalmers, Chemical and Biological Engineering, Life Sciences
FEMS Yeast Research
1567-1356 (ISSN) 1567-1364 (eISSN)
Vol. 14 1 109-118Subject Categories
Chemical Sciences
DOI
10.1111/1567-1364.12112