Approaches to study yeast cell aging and death
Journal article, 2014

For millennia, yeast has been exploited to obtain fermentation products, such as foods and beverages. For c. 50years, yeast has been an established model organism for basic and applied research, and more specifically, for c. 15years, this unicellular organism has been applied to dissect molecular mechanisms of cell aging and programmed cell death. In this review, we present an overview of approaches to study cell aging and death in yeast, including lifespan assessments, calorie restriction, cell viability, survival, and death markers.

span

CHRONOLOGICAL LIFE-SPAN

CALORIE RESTRICTION

replicative life

ALPHA-SYNUCLEIN

STATIONARY-PHASE

CHROMOSOMAL REARRANGEMENTS

SYSTEMS BIOLOGY

chronological life span

PROTEIN-KINASE

MITOCHONDRIAL FISSION

SACCHAROMYCES-CEREVISIAE

yeast survival

Saccharomyces cerevisiae

yeast cell death

MODEL SYSTEM

oxidative stress

Author

M. G. Mirisola

University of Palermo

R. J. Braun

University of Bayreuth

Dina Petranovic Nielsen

Chalmers, Chemical and Biological Engineering, Life Sciences, System Biology

FEMS Yeast Research

1567-1356 (ISSN) 1567-1364 (eISSN)

Vol. 14 1 109-118

Subject Categories

Chemical Sciences

DOI

10.1111/1567-1364.12112

More information

Latest update

4/11/2018