Approaches to study yeast cell aging and death
Artikel i vetenskaplig tidskrift, 2014

For millennia, yeast has been exploited to obtain fermentation products, such as foods and beverages. For c. 50years, yeast has been an established model organism for basic and applied research, and more specifically, for c. 15years, this unicellular organism has been applied to dissect molecular mechanisms of cell aging and programmed cell death. In this review, we present an overview of approaches to study cell aging and death in yeast, including lifespan assessments, calorie restriction, cell viability, survival, and death markers.

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CHRONOLOGICAL LIFE-SPAN

CALORIE RESTRICTION

replicative life

ALPHA-SYNUCLEIN

STATIONARY-PHASE

CHROMOSOMAL REARRANGEMENTS

SYSTEMS BIOLOGY

chronological life span

PROTEIN-KINASE

MITOCHONDRIAL FISSION

SACCHAROMYCES-CEREVISIAE

yeast survival

Saccharomyces cerevisiae

yeast cell death

MODEL SYSTEM

oxidative stress

Författare

M. G. Mirisola

Universita degli Studi di Palermo

R. J. Braun

Universität Bayreuth

Dina Petranovic Nielsen

Chalmers, Kemi- och bioteknik, Livsvetenskaper, Systembiologi

FEMS Yeast Research

1567-1356 (ISSN) 1567-1364 (eISSN)

Vol. 14 1 109-118

Ämneskategorier

Kemi

DOI

10.1111/1567-1364.12112