In situ synthesis of conductive polypyrrole on electrospun cellulose nanofibers: scaffold for neural tissue engineering
Journal article, 2015

This study reports the synthesis of conductive polypyrrole (PPy) on electrospun cellulose nanofibers. The cellulose nanofibers were electrospun via cellulose acetate and surface modified using in situ pyrrole polymerization. PPy adhered to the cellulose nanofiber surface as small particles and caused a 105 fold increase in conductivity compared to unmodified cellulose nanofibers. In addition, tests revealed no cytotoxic potential for the PPy coated cellulose nanofiber materials. In vitro culturing using SH-SY5Y human neuroblastoma cells indicated enhanced cell adhesion on the PPy coated cellulose material. SH-SY5Y cell viability was evident up to 15 days of differentiation and cells adhered to the PPy coated cellulose nanofibers and altered their morphology to a more neuron like phenotype.

Tissue engineering

Cellulose

Electrospinning

Polypyrrole

Fiber

Author

Johannes Thunberg

Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry, Organic Chemistry

Theodoros Kalogeropoulos

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry, Polymer Technology

Volodymyr Kuzmenko

Chalmers, Applied Physics, Electronics Material and Systems Laboratory

Daniel Hägg

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry, Polymer Technology

Sara Johannesson

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry, Polymer Technology

Gunnar Westman

Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry, Organic Chemistry

Paul Gatenholm

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry, Polymer Technology

Cellulose

0969-0239 (ISSN)

Vol. 22 3 1459-1467

Subject Categories

Textile, Rubber and Polymeric Materials

Areas of Advance

Materials Science

DOI

10.1007/s10570-015-0591-5

More information

Latest update

11/23/2018