Fast size-determination of intact bacterial plasmids using nanofluidic channels
Journal article, 2015

We demonstrate how nanofluidic channels can be used as a tool to rapidly determine the number and sizes of plasmids in bacterial isolates. Each step can be automated at low cost, opening up opportunities for general use in microbiology labs.

Author

Karolin Frykholm

Chalmers, Biology and Biological Engineering, Chemical Biology

Lena Nyberg

Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry, Physical Chemistry

E. Lagerstedt

Lund University

C. Noble

Lund University

Joachim Fritzsche

Chalmers, Applied Physics, Chemical Physics

N. Karami

Sahlgrenska University Hospital

T. Ambjornsson

Lund University

L. Sandegren

Uppsala University

Fredrik Westerlund

Chalmers, Biology and Biological Engineering, Chemical Biology

Lab on a Chip - Miniaturisation for Chemistry and Biology

1473-0197 (ISSN) 1473-0189 (eISSN)

Vol. 15 13 2739-2743

Areas of Advance

Nanoscience and Nanotechnology (2010-2017)

Life Science Engineering (2010-2018)

Subject Categories

Biochemistry and Molecular Biology

DOI

10.1039/c5lc00378d

PubMed

25997119

More information

Latest update

4/17/2018