Minimum Information about a Biosynthetic Gene cluster
Review article, 2015

A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.

Author

M. H. Medema

Max Planck Institute for Marine Microbiology

R. Kottmann

Max Planck Institute for Marine Microbiology

P. Yilmaz

Max Planck Institute for Marine Microbiology

F. O. Glöckner

Max Planck Institute for Marine Microbiology

M. Cummings

University of Manchester

J. B. Biggins

Rockefeller University

K. Blin

Technical University of Denmark (DTU)

I. De Bruijn

Netherlands Institute of Ecology

Y. H. Chooi

University of Western Australia

University of California at Los Angeles

J. Claesen

University of California at San Francisco

R. C. Coates

DOE Joint Genome Institute

P. Cruz-Morales

National Polytechnic Institute Mexico

S. Duddela

Saarland University of Applied Sciences

S. Düsterhus

Goethe University Frankfurt

D. J. Edwards

The California State University

D. P. Fewer

University of Helsinki

N. Garg

University of California at San Diego (UCSD)

C. Geiger

Goethe University Frankfurt

J. P. Gomez-Escribano

John Innes Centre

A. Greule

University of Freiburg

A. S. Haines

University of Birmingham

E. J. N. Helfrich

Swiss Federal Institute of Technology in Zürich (ETH)

M. L. Hillwig

University of Pittsburgh

K. Ishida

Hans-Knoll-Institute (HKI)

K. Jungmann

Universität des Saarlandes

A. C. Jones

Gordon and Betty Moore Foundation

C. S. Jones

Roosevelt University

C. Kegler

Goethe University Frankfurt

H. U. Kim

Korea Advanced Institute of Science and Technology (KAIST)

Technical University of Denmark (DTU)

P. Kötter

Goethe University Frankfurt

D. Krug

Universität des Saarlandes

J. Masschelein

KU Leuven

A. V. Melnik

University of California at San Diego (UCSD)

S. M. Mantovani

University of California at San Diego (UCSD)

E. A. Monroe

William Paterson University

M. Moore

Memorial University of Newfoundland

N. Moss

University of California at San Diego (UCSD)

H. W. Nützmann

John Innes Centre

G. Pan

Scripps Research Institute

A. Pati

DOE Joint Genome Institute

D. Petras

Technische Universität Berlin

F. J. Reen

University College Cork

F. Rosconi

Instituto de Investigaciones Biologicas Clemente Estable

Z. Rui

University of California at Berkeley

Z. Tian

Chinese Academy of Sciences

N. J. Tobias

Goethe University Frankfurt

Y. Tsunematsu

University of Shizuoka

Hans-Knoll-Institute (HKI)

P. Wiemann

University of Wisconsin Madison

E. Wyckoff

The University of Texas at Austin

X. Yan

Scripps Research Institute

G. Yim

McMaster University

F. Yu

University of Michigan

Y. Xie

Chinese Academy of Sciences

B. Aigle

National Institute of Agronomic Research (INRA)

A. K. Apel

University of Tübingen

C. J. Balibar

Merck Research Laboratories

E. P. Balskus

Harvard University

F. Barona-Gómez

National Polytechnic Institute Mexico

A. Bechthold

University of Freiburg

H. B. Bode

Goethe University Frankfurt

R. Borriss

Humboldt University of Berlin

S. F. Brady

Rockefeller University

A. A. Brakhage

Hans-Knoll-Institute (HKI)

P. Caffrey

University College Dublin

Y. Q. Cheng

University of North Texas Health Science Center

J. Clardy

Harvard Medical School

R. J. Cox

University of Hanover

University of Bristol

R. De Mot

University of Leuven

S. Donadio

Naicons Srl

M. S. Donia

Princeton University

W. A. Van Der Donk

University of Illinois

The Howard Hughes Medical Institute

P. C. Dorrestein

University of California at San Diego (UCSD)

S. Doyle

Maynooth University

A. J. M. Driessen

University of Groningen

M. Ehling-Schulz

University of Veterinary Medicine Vienna

K. D. Entian

Universität des Saarlandes

M. A. Fischbach

University of California at San Francisco

L. Gerwick

University of California at San Diego (UCSD)

W. H. Gerwick

University of California at San Diego (UCSD)

H. Gross

University of Tübingen

B. Gust

University of Tübingen

C. Hertweck

Hans-Knoll-Institute (HKI)

Friedrich Schiller University Jena

M. Höfte

Ghent university

S. E. Jensen

University of Alberta

J. Ju

Chinese Academy of Sciences

L. Katz

University of California

L. Kaysser

University of Tübingen

J. L. Klassen

University of Connecticut

N. P. Keller

University of Wisconsin Madison

J. Kormanec

Slovak Academy of Sciences

O. P. Kuipers

University of Groningen

T. Kuzuyama

University of Tokyo

N. C. Kyrpides

King Abdulaziz University

DOE Joint Genome Institute

H. J. Kwon

Myongji University

S. Lautru

University of Paris-Sud

R. Lavigne

KU Leuven

C. Y. Lee

University of Arkansas for Medical Sciences

B. Linquan

Shanghai Jiao Tong University

X. Liu

University of Pittsburgh

W. Liu

Chinese Academy of Sciences

A. Luzhetskyy

Universität des Saarlandes

T. Mahmud

Oregon State University

Y. Mast

University of Tübingen

C. Méndez

University of Oviedo

M. Metsä-Ketelä

University of Turku

J. Micklefield

University of Manchester

D. A. Mitchell

University of Illinois

B. S. Moore

University of California at San Diego (UCSD)

L. M. Moreira

University of Lisbon

R. Müller

Universität des Saarlandes

B. A. Neilan

University of New South Wales (UNSW)

M. Nett

Hans-Knoll-Institute (HKI)

Jens B Nielsen

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

F. O'Gara

University College Cork

University of Western Australia

H. Oikawa

Hokkaido University

A. Osbourn

John Innes Centre

M. S. Osburne

Tufts University

B. Ostash

Ivan Franko National University of Lviv

S. M. Payne

The University of Texas at Austin

J. L. Pernodet

University of Paris-Sud

M. Petricek

Academy of Sciences of the Czech Republic v.v.i

J. Piel

Swiss Federal Institute of Technology in Zürich (ETH)

O. Ploux

Paris Diderot University

J. M. Raaijmakers

Netherlands Institute of Ecology

J. A. Salas

University of Oviedo

E. K. Schmitt

Novartis Institutes for BioMedical Research

B. Scott

Massey University

R. F. Seipke

University of Leeds

B. Shen

Scripps Research Institute

D. H. Sherman

University of Michigan

K. Sivonen

University of Helsinki

M. J. Smanski

University of Minnesota

M. Sosio

Naicons Srl

E. Stegmann

University of Tübingen

R. D. Süssmuth

Technische Universität Berlin

K. Tahlan

Memorial University of Newfoundland

C. M. Thomas

University of Birmingham

Y. Tang

University of California at Los Angeles

A. W. Truman

John Innes Centre

M. Viaud

National Institute of Agronomic Research (INRA)

J. D. Walton

Michigan State University

C. T. Walsh

Stanford University

T. Weber

Technical University of Denmark (DTU)

G. P. Van Wezel

Leiden University

B. Wilkinson

John Innes Centre

J. M. Willey

Hofstra University

W. Wohlleben

University of Tübingen

G. D. Wright

McMaster University

C. Zhang

Chinese Academy of Sciences

N. Ziemert

University of Tübingen

S. B. Zotchev

Norwegian University of Science and Technology (NTNU)

R. Breitling

University of Manchester

E. Takano

University of Manchester

M. Hadjithomas

DOE Joint Genome Institute

Nature Chemical Biology

1552-4450 (ISSN) 1552-4469 (eISSN)

Vol. 11 9 625-631

Subject Categories

Biochemistry and Molecular Biology

Bioinformatics and Systems Biology

Areas of Advance

Life Science Engineering (2010-2018)

DOI

10.1038/nchembio.1890

PubMed

26284661

More information

Latest update

7/12/2021