Synthesis of Multiring Fused 2-Pyridones via a Nitrene Insertion Reaction: Fluorescent Modulators of α-Synuclein Amyloid Formation
Journal article, 2015

© 2015 American Chemical Society. An efficient, straightforward method for the synthesis of thiazolo-2-pyridone embedded peptidomimetic polyheterocycles via a catalyst-free, microwave-assisted, intramolecular C-H amination reaction is reported. All the synthesized polyheterocycles were evaluated for their fluorescent properties and effect on α-synuclein amyloid formation.


P. Singh

Umeå University

E. Chorell

Umeå University

K.S. Krishnan

Mannam Memorial NSS College

T. Kindahl

Umeå University

J. Åden

Umeå University

Pernilla Wittung Stafshede

Chalmers, Biology and Biological Engineering, Chemical Biology

F. Almqvist

Umeå University

Organic Letters

1523-7060 (ISSN) 1523-7052 (eISSN)

Vol. 17 24 6194-6197

Subject Categories

Chemical Sciences



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