Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease
Other text in scientific journal, 2017
Plasma mannose levels are elevated in subjects with insulin resistance independently of obesity. Here, we found that elevated plasma mannose levels are strong markers of future risk of several chronic diseases including T2D, CVD, and albuminuria, and that it may contribute to their development rather than just being a novel biomarker.
Insulin Sensitivity
Resistance
Glucose-Tolerance
Author
Adil Mardinoglu
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
A. Stancakova
University of Eastern Finland
L. A. Lotta
University of Cambridge
J. Kuusisto
University of Eastern Finland
Jan Borén
Sahlgrenska University Hospital
M. Bluher
Leipzig University
N. J. Wareham
University of Cambridge
E. Ferrannini
Istituto di Fisiologia Clinica del CNR
P. H. Groop
Biomedicum Helsinki
Baker Heart and Diabetes Institute
Helsinki University Central Hospital
M. Laakso
University of Eastern Finland
C. Langenberg
University of Cambridge
U. Smith
Sahlgrenska University Hospital
Cell Metabolism
1550-4131 (ISSN) 19327420 (eISSN)
Vol. 26 2 281-283Subject Categories
Cell and Molecular Biology
DOI
10.1016/j.cmet.2017.07.006