Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease
Övrig text i vetenskaplig tidskrift, 2017
Plasma mannose levels are elevated in subjects with insulin resistance independently of obesity. Here, we found that elevated plasma mannose levels are strong markers of future risk of several chronic diseases including T2D, CVD, and albuminuria, and that it may contribute to their development rather than just being a novel biomarker.
Insulin Sensitivity
Resistance
Glucose-Tolerance
Författare
Adil Mardinoglu
Chalmers, Biologi och bioteknik, Systembiologi
A. Stancakova
Itä-Suomen Yliopisto
L. A. Lotta
University of Cambridge
J. Kuusisto
Itä-Suomen Yliopisto
Jan Borén
Sahlgrenska universitetssjukhuset
M. Bluher
Universität Leipzig
N. J. Wareham
University of Cambridge
E. Ferrannini
Istituto di Fisiologia Clinica del CNR
P. H. Groop
Biomedicum Helsinki
Baker Heart and Diabetes Institute
Helsinki University Central Hospital
M. Laakso
Itä-Suomen Yliopisto
C. Langenberg
University of Cambridge
U. Smith
Sahlgrenska universitetssjukhuset
Cell Metabolism
1550-4131 (ISSN) 19327420 (eISSN)
Vol. 26 2 281-283Ämneskategorier
Cell- och molekylärbiologi
DOI
10.1016/j.cmet.2017.07.006