Metabolite Depletion Affects Flux Profiling of Cell Lines
Introductory text in journal, 2018

Quantifying the rate of consumption and release of metabolites (i.e., flux profiling) has become integral to the study of cancer. The fluxes as well as the growth of the cells may be affected by metabolite depletion during cultivation.

serine

metabolic modeling

glutamine

cancer

Author

Avlant Nilsson

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

J. R. Haanstra

Free University of Amsterdam

B. Teusink

Free University of Amsterdam

Jens B Nielsen

Technical University of Denmark (DTU)

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Trends in Biochemical Sciences

0968-0004 (ISSN) 0167-7640 (eISSN)

Vol. 43 6 395-397

Subject Categories

Cell Biology

Bioengineering Equipment

Pharmacology and Toxicology

DOI

10.1016/j.tibs.2018.03.009

More information

Latest update

7/5/2018 2