Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies
Review article, 2019

The life sciences are currently being transformed by an unprecedented wave of developments in molecular analysis, which include important advances in instrumental analysis as well as biocomputing. In light of the central role played by metabolism in nutrition, metabolomics is rapidly being established as a key analytical tool in human nutritional studies. Consequently, an increasing number of nutritionists integrate metabolomics into their study designs. Within this dynamic landscape, the potential of nutritional metabolomics (nutrimetabolomics) to be translated into a science, which can impact on health policies, still needs to be realized. A key element to reach this goal is the ability of the research community to join, to collectively make the best use of the potential offered by nutritional metabolomics. This article, therefore, provides a methodological description of nutritional metabolomics that reflects on the state-of-the-art techniques used in the laboratories of the Food Biomarker Alliance (funded by the European Joint Programming Initiative “A Healthy Diet for a Healthy Life” (JPI HDHL)) as well as points of reflections to harmonize this field. It is not intended to be exhaustive but rather to present a pragmatic guidance on metabolomic methodologies, providing readers with useful “tips and tricks” along the analytical workflow.

NMR

GC–MS

metabolomics

LC–MS

nutrition

Author

Marynka M. Ulaszewska

Istituto Agrario San Michele all'Adige

Christoph H. Weinert

Max Rubner-Institut, Germany

Alessia Trimigno

University of Bologna

Reto Portmann

Forschungsanstalt Agroscope Changins-Wadenswil

Cristina Andres-Lacueva

University of Barcelona

René Badertscher

Forschungsanstalt Agroscope Changins-Wadenswil

Lorraine Brennan

University College Dublin

Carl Brunius

Chalmers, Biology and Biological Engineering, Food and Nutrition Science

Other publications Research

Achim Bub

Max Rubner-Institut, Germany

Francesco Capozzi

University of Bologna

Marta Cialiè Rosso

University of Turin

Chiara E. Cordero

University of Turin

Hannelore Daniel

Technical University of Munich

Stéphanie Durand

Universite d' Auvergne Clermont-FD 1

Bjoern Egert

Max Rubner-Institut, Germany

Paola G. Ferrario

Max Rubner-Institut, Germany

Edith J.M. Feskens

Wageningen University and Research

Pietro Franceschi

Istituto Agrario San Michele all'Adige

Mar Garcia-Aloy

University of Barcelona

Franck Giacomoni

Universite d' Auvergne Clermont-FD 1

Pieter Giesbertz

Technical University of Munich

Raúl González-Domínguez

University of Barcelona

K. Hanhineva

University of Eastern Finland

Lieselot Y. Hemeryck

Ghent university

Joachim Kopka

Max Planck Society

Sabine E. Kulling

Max Rubner-Institut, Germany

Rafael Llorach

University of Barcelona

Claudine Manach

Universite d' Auvergne Clermont-FD 1

Fulvio Mattivi

Istituto Agrario San Michele all'Adige

University of Trento

Carole Migné

Universite d' Auvergne Clermont-FD 1

Linda H. Münger

Forschungsanstalt Agroscope Changins-Wadenswil

Beate Ott

Technical University of Munich

Gianfranco Picone

University of Bologna

Grégory Pimentel

Forschungsanstalt Agroscope Changins-Wadenswil

E. Pujos-Guillot

Universite d' Auvergne Clermont-FD 1

Samantha Riccadonna

Istituto Agrario San Michele all'Adige

Manuela J. Rist

Max Rubner-Institut, Germany

Caroline Rombouts

Ghent university

Josep Rubert

Istituto Agrario San Michele all'Adige

Thomas Skurk

Technical University of Munich

Pedapati S.C. Sri Harsha

University College Dublin

Lieven Van Meulebroek

Ghent university

Lynn Vanhaecke

Ghent university

Rosa Vázquez-Fresno

University of Alberta

David S. Wishart

University of Alberta

Guy Vergeres

Forschungsanstalt Agroscope Changins-Wadenswil

Molecular Nutrition and Food Research

1613-4125 (ISSN)

Vol. 63 1 1800384

Subject Categories

Social Sciences Interdisciplinary

Other Humanities not elsewhere specified

Architecture

DOI

10.1002/mnfr.201800384

Publication data connected to DOI

PubMed

30176196

More information

Latest update

11/22/2019

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