Carl Brunius

Associate Professor at Food and Nutrition Science

Carl Brunius investigates connections between food and health, to develop approaches for precision nutrition, i.e. healthy food tailored for individual requirements. His research focuses on Big Data methodology to investigate and understand how metabolites and intestinal flora vary and interact in relation to diet and health. The aim is to identify markers for dietary exposure and for metabotypes, ie groups of individuals with similar metabolic regulation in relation to diet, and to understand and quantitate the metabotype determinants using computational metabolomics and microbiota analyses.

Source: chalmers.se
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Showing 33 publications

2020

Consumption of whole grain/bran rye instead of refined wheat decrease concentrations of TNF-R2, e-selectin, and endostatin in an exploratory study in men with prostate cancer

Galia Zamaratskaia, Nor Adila Mhd Omar, Carl Brunius et al
Clinical Nutrition. Vol. 39 (1), p. 159-165
Introductory text in journal
2020

A case report of switching from specific vendor-based to R-based pipelines for untargeted LC-MS metabolomics

Álvaro Fernández-Ochoa, Rosa Quirantes-Piné, Isabel Borrás-Linares et al
Metabolites. Vol. 10 (1)
Journal article
2020

Professional dental cleaning in dogs: clinical routines among Swedish veterinarians and veterinary nurses

Karolina Brunius Enlund, Michaela Karlsson, Carl Brunius et al
Acta Veterinaria Scandinavica. Vol. 62 (1)
Journal article
2020

Metabolomic profiles of mid-trimester amniotic fluid are not associated with subsequent spontaneous preterm delivery or gestational duration at delivery

Maria Hallingstrom, Malin Barman, Otto Savolainen et al
Journal of Maternal-Fetal and Neonatal Medicine. Vol. In Press
Journal article
2020

Plasma metabolite biomarkers of boiled and filtered coffee intake and their association with type 2 diabetes risk

Lin Shi, Carl Brunius, Ingegerd Johansson et al
Journal of Internal Medicine. Vol. 287 (4), p. 405-421
Journal article
2020

Dog Owners' Perspectives on Canine Dental Health - A Questionnaire Study in Sweden

Karolina Brunius Enlund, Carl Brunius, Jeanette Hanson et al
Frontiers in Veterinary Science. Vol. 7
Journal article
2020

In-plate toxicometabolomics of single zebrafish embryos

Anton Ribbenstedt, Malte Posselt, Carl Brunius et al
Molecular Omics. Vol. 16 (3), p. 185-194
Journal article
2020

An LC-QToF MS based method for untargeted metabolomics of human fecal samples

Ken Cheng, Carl Brunius, Rikard Fristedt et al
Metabolomics. Vol. 16 (4)
Journal article
2020

Metabolic Disturbances in Urinary and Plasma Samples from Seven Different Systemic Autoimmune Diseases Detected by HPLC-ESI-QTOF-MS

Alvaro Fernandez-Ochoa, Carl Brunius, Isabel Borras-Linares et al
Journal of Proteome Research. Vol. 19 (8), p. 3220-3229
Journal article
2020

Dental home care in dogs-a questionnaire study among Swedish dog owners, veterinarians and veterinary nurses

Karolina Brunius Enlund, Carl Brunius, Jeanette Hanson et al
BMC Veterinary Research. Vol. 16 (1)
Journal article
2020

Effects of a long-term lifestyle intervention on metabolically healthy women with obesity: Metabolite profiles according to weight loss response

Magali Palau-Rodriguez, Mar Garcia-Aloy, Antonio Miñarro et al
Clinical Nutrition. Vol. 39 (1), p. 215-224
Journal article
2020

“Notame”: Workflow for non-targeted LC-MS metabolic profiling

Anton Klåvus, Marietta Kokla, Stefania Noerman et al
Metabolites. Vol. 10 (4)
Journal article
2020

Perspective: Metabotyping—A Potential Personalized Nutrition Strategy for Precision Prevention of Cardiometabolic Disease

Marie Palmnäs, Carl Brunius, Lin Shi et al
Advances in nutrition (Bethesda, Md.). Vol. 11 (3), p. 524-532
Journal article
2020

Effects of whole-grain wheat, rye, and lignan supplementation on cardiometabolic risk factors in men with metabolic syndrome: A randomized crossover trial

Anne Kirstine Eriksen, Carl Brunius, Mohsen Mazidi et al
American Journal of Clinical Nutrition. Vol. 111 (4), p. 864-876
Journal article
2019

Carbonic Anhydrase 6 Gene Variation influences Oral Microbiota Composition and Caries Risk in Swedish adolescents

A. Esberg, S. Haworth, Carl Brunius et al
Scientific Reports. Vol. 9
Journal article
2019

Joint Analysis of Metabolite Markers of Fish Intake and Persistent Organic Pollutants in Relation to Type 2 Diabetes Risk in Swedish Adults

Lin Shi, Carl Brunius, Ingvar A. Bergdahl et al
Journal of Nutrition. Vol. 149 (8), p. 1413-1423
Journal article
2019

Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies

Marynka M. Ulaszewska, Christoph H. Weinert, Alessia Trimigno et al
Molecular Nutrition and Food Research. Vol. 63 (1)
Review article
2019

Visualization and interpretation of multivariate associations with disease risk markers and disease risk—The triplot

Tessa Schillemans, Lin Shi, Xin Liu et al
Metabolites. Vol. 9 (7)
Journal article
2019

Variable selection and validation in multivariate modelling

Lin Shi, Johan A. Westerhuis, Johan Rosén et al
Bioinformatics. Vol. 35 (6), p. 972-980
Journal article
2019

The H-1 NMR serum metabolomics response to a two meal challenge: a cross-over dietary intervention study in healthy human volunteers

Millie Radjursoga, Helen M. Lindqvist, Anders Pedersen et al
Nutrition Journal. Vol. 18
Journal article
2019

Development and validation of two questionnaires: Dental home care and dental health in Swedish dogs

Karolina Brunius Enlund, Carl Brunius, Jeanette Hanson et al
PLoS ONE. Vol. 14 (1)
Journal article
2019

Factors Explaining Interpersonal Variation in Plasma Enterolactone Concentrations in Humans

Elin Hålldin, Anne Kirstine Eriksen, Carl Brunius et al
Molecular Nutrition and Food Research. Vol. 63 (16)
Review article
2018

Impact of location on composition of selected phytochemicals in wild sea buckthorn (Hippophae rhamnoides)

Samanthi R.P. Madawala, Carl Brunius, Alok Adholeya et al
Journal of Food Composition and Analysis. Vol. 72, p. 115-121
Journal article
2018

Appetite and Subsequent Food Intake Were Unaffected by the Amount of Sourdough and Rye in Soft Bread-A Randomized Cross-Over Breakfast Study

Kia Noehr Iversen, Daniel P. Johansson, Carl Brunius et al
Nutrients. Vol. 10 (11)
Journal article
2018

Plasma metabolites associated with type 2 diabetes in a Swedish population: a case-control study nested in a prospective cohort

Lin Shi, Carl Brunius, Marko Lehtonen et al
Diabetologia. Vol. 61 (4), p. 849-861
Journal article
2018

Impact in Plasma Metabolome as Effect of Lifestyle Intervention for Weight-Loss Reveals Metabolic Benefits in Metabolically Healthy Obese Women

Enrique Almanza-Aguilera, Carl Brunius, M. Rosa Bernal-Lopez et al
Journal of Proteome Research. Vol. 17 (8), p. 2600-2610
Journal article
2018

Untargeted 1H NMR-Based Metabolomics Analysis of Urine and Serum Profiles after Consumption of Lentils, Chickpeas, and Beans: An Extended Meal Study to Discover Dietary Biomarkers of Pulses

Francisco Madrid-Gambin, Carl Brunius, Mar Garcia-Aloy et al
Journal of Agricultural and Food Chemistry. Vol. 66 (27), p. 6997-7005
Journal article
2018

Plasma metabolites associated with healthy Nordic dietary indexes and risk of type 2 diabetes-a nested case-control study in a Swedish population

Lin Shi, Carl Brunius, Ingegerd Johansson et al
American Journal of Clinical Nutrition. Vol. 108 (3), p. 564-575
Journal article
2017

Targeted metabolomics reveals differences in the extended postprandial plasma metabolome of healthy subjects after intake of whole-grain rye porridges versus refined wheat bread.

Lin Shi, Carl Brunius, Magnus Lindelöf et al
Molecular nutrition & food research. Vol. 61 (7 (SI)), p. Article no. 1600924 -
Journal article
2017

Targeted and untargeted metabolomics for specific food intake assessment whole grains as an example

Carl Brunius, Huaxing Wu, Rikard Landberg
Advances in the Assessment of Dietary Intake, p. 315-336
Book chapter
2017

Prediction and modeling of pre-analytical sampling errors as a strategy to improve plasma NMR metabolomics data

Carl Brunius, Anders Pedersen, Daniel Malmodin et al
Bioinformatics. Vol. 33 (22), p. 3567-3574
Journal article

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Showing 4 research projects

2020–2022

Discovery and valdiation of novel biomarkers of gut microbiota, diet and their interactions associated with type 2 diabetes risk

Rikard Landberg Food and Nutrition Science
Carl Brunius Food and Nutrition Science
Swedish Research Council (VR)

2018–2019

Kost, miljöföroreningar och risk för typ 2-diabetes

Carl Brunius Food and Nutrition Science
Dr. P. Håkansson’s Foundation

2018–2021

DiGuMet Project: Diet x gut microbiome-based metabotypes to determine cardio-metabolic risk and tailor intervention strategies for improved health

Rikard Landberg Food and Nutrition Science
Carl Brunius Food and Nutrition Science
Marie Palmnäs Food and Nutrition Science
Formas

2018–2020

Riskprediktion och tidig upptäckt av tjock- och ändtarmscancer, en integrativ molekylärepidemiologisk approach

Carl Brunius Food and Nutrition Science
Swedish Research Council (VR)

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