Present and Future of Surface-Enhanced Raman Scattering
Review article, 2020

The discovery of the enhancement of Raman scattering by molecules adsorbed on nanostructured metal surfaces is a landmark in the history of spectroscopic and analytical techniques. Significant experimental and theoretical effort has been directed toward understanding the surface-enhanced Raman scattering (SERS) effect and demonstrating its potential in various types of ultrasensitive sensing applications in a wide variety of fields. In the 45 years since its discovery, SERS has blossomed into a rich area of research and technology, but additional efforts are still needed before it can be routinely used analytically and in commercial products. In this Review, prominent authors from around the world joined together to summarize the state of the art in understanding and using SERS and to predict what can be expected in the near future in terms of research, applications, and technological development. This Review is dedicated to SERS pioneer and our coauthor, the late Prof. Richard Van Duyne, whom we lost during the preparation of this article. ©

surface-enhanced Raman scattering

biosensing

SEIRA

hot electrons

TERS

nanomedicine

charge transfer

SERS tags

chemosensors

catalysis

Author

Judith Langer

CIBER Bioingenieria, Biomateriales y Nanomedicina

Dorleta Jimenez De Aberasturi

CIBER Bioingenieria, Biomateriales y Nanomedicina

Javier Aizpurua

Donostia International Physics Center

Ramon A. Alvarez-Puebla

Rovira i Virgili University

Catalan Institution for Research and Advanced Studies

Baptiste Auguié

Victoria University of Wellington

Dodd-Walls Centre for Photonic and Quantum Technologies

MacDiarmid Institute for Advanced Materials and Nanotechnology

Jeremy J. Baumberg

University of Cambridge

Guillermo C. Bazan

University of California

Steven E.J. Bell

Queen's University Belfast

A. Boisen

Technical University of Denmark (DTU)

Alexandre G. Brolo

University of Victoria

Jaebum Choo

Chung-Ang University

Dana Cialla-May

Friedrich Schiller University Jena

Leibniz-Institut Für Photonische Technologien E.V.

Volker Deckert

Friedrich Schiller University Jena

Leibniz-Institut Für Photonische Technologien E.V.

Laura Fabris

Rutgers University

Karen Faulds

University of Strathclyde

F. J. García de Abajo

Barcelona Institute of Science and Technology (BIST)

Catalan Institution for Research and Advanced Studies

Royston Goodacre

University of Liverpool

Duncan Graham

University of Strathclyde

Amanda J. Haes

University of Iowa

Christy L. Haynes

University of Minnesota

Christian Huck

Heidelberg University

Tamitake Itoh

National Institute of Advanced Industrial Science and Technology (AIST)

Mikael Käll

Chalmers, Physics, Bionanophotonics

Janina Kneipp

Humboldt University of Berlin

Nicholas A. Kotov

University of Michigan

Hua Kuang

Jiangnan University

Eric C. Le Ru

MacDiarmid Institute for Advanced Materials and Nanotechnology

Dodd-Walls Centre for Photonic and Quantum Technologies

Victoria University

Hiang Kwee Lee

Stanford University

Nanyang Technological University

Jian Feng Li

Xiamen University

Xing Yi Ling

Nanyang Technological University

S. A. Maier

Ludwig Maximilian University of Munich (LMU)

Thomas Mayerhöfer

Leibniz-Institut Für Photonische Technologien E.V.

Friedrich Schiller University Jena

Martin Moskovits

University of California

Kei Murakoshi

Hokkaido University

Jwa Min Nam

Seoul National University

Shuming Nie

University of Illinois

Yukihiro Ozaki

Kwansei Gakuin University

Isabel Pastoriza-Santos

University of Vigo

Jorge Perez-Juste

University of Vigo

Juergen Popp

Leibniz-Institut Für Photonische Technologien E.V.

Friedrich Schiller University Jena

Annemarie Pucci

Heidelberg University

Stephanie Reich

Freie Universität Berlin

Bin Ren

Xiamen University

G.C. Schatz

Northwestern University

Timur Shegai

Chalmers, Physics, Bionanophotonics

Sebastian Schlücker

University of Duisburg-Essen

Li Lin Tay

National Research Council Canada

K. George Thomas

Indian Institute of Science

Zhong Qun Tian

Xiamen University

R. P. Van Duyne

Northwestern University

Tuan Vo-Dinh

Duke University

Yue Wang

Northeastern University China

Katherine A. Willets

Temple University

Chuanlai Xu

Jiangnan University

H. Xu

Wuhan University

Yikai Xu

Queen's University Belfast

Yuko S. Yamamoto

Japan Advanced Institute of Science and Technology (JAIST)

Bing Zhao

Jilin University

Luis M. Liz-Marzán

CIBER Bioingenieria, Biomateriales y Nanomedicina

Basque Foundation for Science (Ikerbasque)

ACS Nano

1936-0851 (ISSN) 1936-086X (eISSN)

Vol. 14 1 28-117

Subject Categories (SSIF 2011)

Other Engineering and Technologies not elsewhere specified

Atom and Molecular Physics and Optics

Materials Chemistry

Condensed Matter Physics

DOI

10.1021/acsnano.9b04224

More information

Latest update

10/29/2025