Promiscuous phosphoketolase and metabolic rewiring enables novel non-oxidative glycolysis in yeast for high-yield production of acetyl-CoA derived products
Journal article, 2020
Mathematical modelling
Saccharomyces cerevisiae
Synthetic biology
Non-oxidative glycolysis
3-Hydroxypropionic acid
Metabolic engineering
Author
John Hellgren
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
Novo Nordisk Foundation
Alexei Godina
Total S.A.
Jens B Nielsen
BioInnovation Institute
Novo Nordisk Foundation
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
Verena Siewers
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
Novo Nordisk Foundation
Metabolic Engineering
1096-7176 (ISSN) 1096-7184 (eISSN)
Vol. 62 150-160Subject Categories
Other Basic Medicine
Microbiology
Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
DOI
10.1016/j.ymben.2020.09.003
PubMed
32911054