Controlling Chemistry in Dynamic Nanoscale Systems
Conference contribution, 2010

The biological cell, the fundamental building block of the living world, is a complex maze of compartmentalized biochemical reactors that embed tens of thousands of chemical reactions running in parallel. Several, if not all, reactors are systematically interconnected by a web of nanofluidic transporters, such as nanotubes, vesicles, and membrane pores with ever-changing shapes and structures [1]. To initiate, terminate, or control chemical reactions, small-scale poly-/pleiomorphic systems undergo rapid and violent shape changes with energy barriers close to kBT , where, due to the small dimensions, diffusional mixing of reactants is rapid. The geometry, i.e. volume, and shape changes can be utilized to control both kinetic and thermodynamic properties of the system. This is in sharp contrast to the man-made macroscopic bioreactors, in which mixing of reactants is aided by mechanical means, such as stirring or sonication, under the assumption that reactions take place in volumes that do not change over time. Such reaction volumes are compact, like a sphere, a cube, or a cylinder, and do not provide for variation of shape. Ordinarily, reaction rates, mechanisms, and thermodynamic properties of chemical reactions in condensed media are based on these assumptions. A number of important questions and challenges arise from these facts. For example, how will we achieve fundamental understanding of how reactor shape affects chemistry on the nanoscale, how do we develop appropriate and powerful experimental model systems, and last but not least what impact will this knowledge have on the design and function of nanotechnological devices with new operation modes derived from natural principles.

Author

Aldo Jesorka

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Ludvig Lizana

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Zoran Konkoli

Chalmers, Applied Physics, Electronics Material and Systems Laboratory

Ilja Czolkos

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Owe Orwar

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Springer Series in Chemical Physics

0172-6218 (ISSN)

Vol. 96 449-468

Subject Categories

Chemical Sciences

DOI

10.1007/978-3-642-02597-6_23

ISBN

978-3-642-02596-9

More information

Created

10/7/2017