Probing Physical Properties of a DNA- Protein Complex Using Nanofluidic Channels
Journal article, 2014

A method to investigate physical properties of a DNA-protein complex in solution is demonstrated. By using tapered nanochannels and lipid passivation the persistence length of a RecA filament formed on double-stranded DNA is determined to 1.15 μm, in agreement with the literature, without attaching protein or DNA to any handles or surfaces. © 2014 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.

Author

Karolin Frykholm

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Other publications Research

Mohammadreza Alizadehheidari

Chalmers, Chemical and Biological Engineering, Physical Chemistry

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Joachim Fritzsche

Chalmers, Applied Physics, Chemical Physics

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Jens Wigenius

Chalmers, Chemical and Biological Engineering, Physical Chemistry

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M. Modesti

Centre national de la recherche scientifique (CNRS)

Institut Paoli-Calmettes

Inserm Transfert

F. Persson

Uppsala University

Inserm Transfert

Fredrik Westerlund

Chalmers, Chemical and Biological Engineering, Physical Chemistry

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Small

1613-6810 (ISSN) 1613-6829 (eISSN)

Vol. 10 5 884-887

Areas of Advance

Nanoscience and Nanotechnology (2010-2017)

Life Science Engineering (2010-2018)

Subject Categories

Biophysics

DOI

10.1002/smll.201302028

Publication data connected to DOI

More information

Latest update

9/7/2018 1

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