Metabolite Depletion Affects Flux Profiling of Cell Lines
Other text in scientific journal, 2018
Quantifying the rate of consumption and release of metabolites (i.e., flux profiling) has become integral to the study of cancer. The fluxes as well as the growth of the cells may be affected by metabolite depletion during cultivation.
serine
metabolic modeling
glutamine
cancer
Author
Avlant Nilsson
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
J. R. Haanstra
Vrije Universiteit Amsterdam
B. Teusink
Vrije Universiteit Amsterdam
Jens B Nielsen
Technical University of Denmark (DTU)
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
Trends in Biochemical Sciences
0968-0004 (ISSN) 13624326 (eISSN)
Vol. 43 6 395-397Subject Categories
Cell Biology
Bioengineering Equipment
Pharmacology and Toxicology
DOI
10.1016/j.tibs.2018.03.009