Kinetic recognition of AT-rich DNA by ruthenium complexes
Journal article, 2007

(Figure Presented) Finding AT tracts: High selectivity for long AT sequences can be attained through kinetically controlled DNA threading intercalation by binuclear ruthenium (II) complexes (see picture). The rate of intercalation is strongly correlated to the number of consecutive AT base pairs and is up to 2500-times higher with poly-(dAdT) 2 than with mixed-sequence DNA. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

TRIS(PHENANTHROLINE)RUTHENIUM(II)

STEREOSELECTIVITY

luminescence

SPECIFICITY

LIGANDS

MINOR-GROOVE

DISSOCIATION

SEQUENCE

kinetics

BINDING

DNA recognition

MODE

intercalation

THREADING INTERCALATION

ruthenium

Author

Pär Nordell

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Other publications Research

Fredrik Westerlund

Chalmers

Other publications Research

Marcus Wilhelmsson

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Other publications Research

Bengt Nordén

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Other publications Research

Per Lincoln

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Other publications Research

Angewandte Chemie - International Edition

1433-7851 (ISSN) 1521-3773 (eISSN)

Vol. 46 13 2203-2206

Subject Categories

Physical Chemistry

DOI

10.1002/anie.200604294

Publication data connected to DOI

More information

Latest update

9/10/2018

Feedback and support

If you have questions, need help, find a bug or just want to give us feedback you may use this form, or contact us per e-mail research.lib@chalmers.se or by phone 46 (0)31-772 3744.

About

Research.chalmers.se contains research information from Chalmers University of Technology, Sweden. It includes information on projects, publications, research funders and collaborations.

More about coverage period and what is publicly available

Privacy and cookies

Links

Chalmers Library
Chalmers Research
Research projects at chalmers.se

Chalmers University of Technology

SE-412 96 GOTHENBURG, SWEDEN
PHONE: +46 (0)31-772 10 00
WWW.CHALMERS.SE