A comparison between the transfer function of ABP to ICP and compensatory reserve index in TBI
Artikel i vetenskaplig tidskrift, 2008

BACKGROUND: The transfer functions which map the arterial blood pressure to the intracranial pressure and the compensatory reserve index have been investigated by various groups to evaluate the brain compliance of patients with traumatic brain injury. The focus of this study has been to assess the capability of both the above mentioned methods to monitor the intracranial compliance in patients suffering from brain swelling. MATERIALS AND METHODS: Clinical data was collected from sixteen traumatic brain injury patients and split into 4 min segments. For each segment, both the magnitude of the empirical transfer function at the fundamental cardiac frequency and the compensatory reserve index were extracted. FINDINGS: The mean values of the compensatory reserve index and the magnitude of the transfer function which scored higher than 0.7 and 0.1 respectively were recorded for all patients suffering from brain swelling. By comparing the histogram of the magnitude of the transfer function at the fundamental cardiac frequency with the histogram of the compensatory reserve index for all patients, a positive correlation between the mean values and a negative correlation among their variances were observed. The linear correlation between the mean values was estimated at r = 0.82 (p < 0.0001). CONCLUSIONS: These observations suggest that to evaluate the intracranial compensatory reserve, the magnitude of 0.1 could be a useful threshold for the transfer function at the fundamental cardiac frequency.

middle aged

pathophysiology

Severity of Illness Index

physiology

Time Factors

male

time

comparative study

hospitalization

intracranial pressure

Young Adult

adult

Humans

female

Computer-Assisted

article

signal processing

brain injury

Cerebrovascular Circulation

adolescent

aged

human

Signal Processing

blood pressure

brain circulation

Brain Injuries

Författare

Sima Shahsavari

Chalmers, Signaler och system, Signalbehandling och medicinsk teknik, Signalbehandling

Tomas McKelvey

Chalmers, Signaler och system, Signalbehandling och medicinsk teknik, Signalbehandling

T. Skoglund

Sahlgrenska universitetssjukhuset

Bertil Rydenhag

Sahlgrenska universitetssjukhuset

Acta Neurochirurgica, Supplement

0065-1419 (ISSN)

Vol. 102 9-13

Ämneskategorier

Data- och informationsvetenskap

DOI

10.1007/978-3-211-85578-2_2

PubMed

19388279

ISBN

9783211855775