Transition-Metal-Catalyzed Propargylic Substitution
Artikel i vetenskaplig tidskrift, 2009
(Chemical Equation Presented) Keen for a share in the glory: Until recently, the title reaction stood in the shadows, its famous sister, catalytic allylic substitution, in the limelight. Catalytic propargylic substitution has now emerged as an efficient transformation that can be catalyzed by a variety of transition metals (see picture). Among the recent developments are copper-catalyzed asymmetric propargylic amination reactions. Nu = nucleophile © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
acetates
alkylation
transition metals
propargylic
amination
nucleophilic substitution
asymmetric catalysis
complexes
alkynes
amines
enoxysilanes
alcohols
esters
nucleophilic-substitution
substitution
acetone
Författare
N. Ljungdahl
Chalmers
Nina Kann
Chalmers, Kemi- och bioteknik, Organisk kemi
Angewandte Chemie - International Edition
1433-7851 (ISSN) 1521-3773 (eISSN)
Vol. 48 4 642-644Ämneskategorier
Fysikalisk kemi
Kemi
DOI
10.1002/anie.200804114