Transition-Metal-Catalyzed Propargylic Substitution
Artikel i vetenskaplig tidskrift, 2009

(Chemical Equation Presented) Keen for a share in the glory: Until recently, the title reaction stood in the shadows, its famous sister, catalytic allylic substitution, in the limelight. Catalytic propargylic substitution has now emerged as an efficient transformation that can be catalyzed by a variety of transition metals (see picture). Among the recent developments are copper-catalyzed asymmetric propargylic amination reactions. Nu = nucleophile © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

acetates

alkylation

transition metals

propargylic

amination

nucleophilic substitution

asymmetric catalysis

complexes

alkynes

amines

enoxysilanes

alcohols

esters

nucleophilic-substitution

substitution

acetone

Författare

N. Ljungdahl

Chalmers

Nina Kann

Chalmers, Kemi- och bioteknik, Organisk kemi

Angewandte Chemie - International Edition

1433-7851 (ISSN) 1521-3773 (eISSN)

Vol. 48 4 642-644

Ämneskategorier

Fysikalisk kemi

Kemi

DOI

10.1002/anie.200804114