Chemical measurements in Drosophila
Artikel i vetenskaplig tidskrift, 2009

The fruit fly, Drosophila melanogaster, has been extensively used as a model organism in genetics research and has significantly contributed to understanding molecular, cellular and evolutionary aspects of human behavior. Recently, research has focused on developing analytical methods to obtain highly sensitive chemical quantification along with spatiotemporal information from Drosophila melanogaster. We review a number of these advances in capillary electrophoresis, high-performance liquid chromatography, mass spectrometry, and technologies involving intact organisms, including in vivo electrochemistry.

Mass spectrometry

High-performance liquid chromatography

Larvae

Micellar electrokinetic chromatography

in vivo electrochemistry

Drosophila

Microfluidics

RNA interference

Galactosidase-4-upstream activating sequences

RNAi

DAT

GAL4-UAS

Capillary electrophoresis

Dopamine transporter

MEMS-based system

Embryo

Författare

Monique A. Makos

Nicholas J. Kuklinski

Göteborgs universitet

M. L. Heien

Andrew Ewing

Göteborgs universitet

E. C. Berglund

Göteborgs universitet

TrAC - Trends in Analytical Chemistry

0165-9936 (ISSN)

Vol. 28 1223-1234

Ämneskategorier

Kemi