Fluorescence Enhancement of Single DNA Molecules Confined in Si/SiO2 Nanochannels
Artikel i vetenskaplig tidskrift, 2010
We demonstrate that the detected emission intensity from YOYO- labeled DNA molecules confined in 180 nm deep Si/SiO2 nano- funnels changes significantly and not monotonically with the width of the funnel. This effect may be of importance for quantitative fluorescence microscopy and for experiments with a tight photon budget.
Författare
Fredrik Westerlund
Göteborgs universitet
Fredrik Persson
Göteborgs universitet
Anders Kristensen
J. O. Tegenfeldt
Göteborgs universitet
Lab on a Chip - Miniaturisation for Chemistry and Biology
1473-0197 (ISSN) 1473-0189 (eISSN)
Vol. 10 16 2049-2051Ämneskategorier
Den kondenserade materiens fysik
DOI
10.1039/c004878j