Fredrik Westerlund

Professor vid Kemisk biologi

Fredrik Westerlunds forskargrupp studerar enstaka DNA-molekyler in nanokanaler med hjälp av fluorescensmikroskopi. Fokus ligger både på att utveckla nya metoder för att kartlägga DNA sekvenser så väl som att studera DNA-proteininteraktioner.







Källa: chalmers.se
Image of Fredrik Westerlund

Visar 188 publikationer

2024

Xrs2/NBS1 promote end-bridging activity of the MRE11-RAD50 complex

Carl Ivar Möller, Rajhans Sharma, Robin Öz et al
Biochemical and Biophysical Research Communications. Vol. 695
Artikel i vetenskaplig tidskrift
2024

Thermodynamics and kinetics of the B-S transition in the wild-type and base-modified DNA

Ioulia Rouzina, Vinoth Sundar Rajan, Sune Levin et al
Biophysical Journal. Vol. 123 (3), p. 498A-499A
Övrigt konferensbidrag
2024

Fluorescence Microscopy of Nanochannel-Confined DNA

Sriram Kesarimangalam, Fredrik Persson, Joachim Fritzsche et al
Methods in Molecular Biology. Vol. 2694, p. 175-202
Kapitel i bok
2024

Nanofluidics for analysing DNA-protein interactions on the single DNA molecule level

Fredrik Westerlund
Biophysical Journal. Vol. 123 (3), p. 3A-4A
Övrigt konferensbidrag
2024

Nanofluidics highlights importance of CtIP's tetrameric structure for DNA repair

Carl Ivar Möller, Sriram Kesarimangalam, Ilaria Ceppi et al
Biophysical Journal. Vol. 123 (3), p. 148A-148A
Övrigt konferensbidrag
2024

Photophysical image analysis: Unsupervised probabilistic thresholding for images from electron-multiplying charge-coupled devices

Jens Krog, Albertas Dvirnas, Oskar E. Ström et al
PLoS ONE. Vol. 19 (4 April)
Artikel i vetenskaplig tidskrift
2024

Comparison of CTX-M encoding plasmids present during the early phase of the ESBL pandemic in western Sweden

Moa Wranne, N. Karami, Sriram Kesarimangalam et al
Scientific Reports. Vol. 14 (1), p. 11880-
Artikel i vetenskaplig tidskrift
2023

Identification and characterization of plasmids carrying the mobile colistin resistance gene mcr-1 using optical DNA mapping

Sriram Kesarimangalam, Moa Wranne, Tsegaye Sewunet et al
JAC-Antimicrobial Resistance. Vol. 5 (1)
Artikel i vetenskaplig tidskrift
2023

Probing physical properties of single amyloid fibrils using nanofluidic channels

Nima Sasanian, Sriram Kesarimangalam, Marziyeh Ghaeidamini et al
European Biophysics Journal. Vol. 52 (SUPPL 1), p. S205-S205
Övrigt konferensbidrag
2023

Plasmonic polymer nanoantenna arrays for electrically tunable and electrode-free metasurfaces

Seunghyun Lee, Daseul Jeong, Sriram Kesarimangalam et al
Journal of Materials Chemistry A. Vol. 11 (40), p. 21569-21576
Artikel i vetenskaplig tidskrift
2023

Single molecule experiments highlight the role of NBS1 and Xrs2 in DNA tethering by MRN and MRX

Carl Ivar Möller, Giordano Reginato, Elda Cannavo et al
European Biophysics Journal. Vol. 52 (1 (suppl.)), p. S197-S197
Övrig text i vetenskaplig tidskrift
2023

A Click Chemistry-Based Artificial Metallo-Nuclease

Alex Gibney, Raphael E.F. de Paiva, Vandana Singh et al
Angewandte Chemie - International Edition. Vol. 62 (38)
Artikel i vetenskaplig tidskrift
2023

Strain-level bacterial typing directly from patient samples using optical DNA mapping

My Nyblom, Anna Johnning, Karolin Frykholm et al
Communications Medicine. Vol. 3 (31)
Artikel i vetenskaplig tidskrift
2023

A single-molecule view on non-homologous end-joining in bacteria

Fredrik Westerlund, Evgeniya Pavlova, Anusha Budida et al
European Biophysics Journal. Vol. 52 (SUPPL 1), p. S213-S213
Övrigt konferensbidrag
2023

Short talk Studying the stability and conformational dynamics of the SARS-CoV-2 SL4 RNA hairpin combining base analogues and optical tweezers

Vinoth Sundar Rajan, Anna Wiktoria Wypijewska Del Nogal, Sune Levin et al
European Biophysics Journal. Vol. 52 (Suppl 1), p. S42-S42
Övrig text i vetenskaplig tidskrift
2023

Exploring the conformational dynamics of the SARS-CoV-2 SL4 hairpin by combining optical tweezers and base analogues

Vinoth Sundar Rajan, Anna Wiktoria Wypijewska Del Nogal, Sune Levin et al
Nanoscale. Vol. 16 (2), p. 752-764
Artikel i vetenskaplig tidskrift
2023

Thermodynamics and kinetics of the B-S transition in base-modified DNA

Vinoth Sundar Rajan, Sune Levin, M. J. McCauley et al
Biophysical Journal. Vol. 122 (3S1)
Artikel i vetenskaplig tidskrift
2023

Polymer Brushes on Silica Nanostructures Prepared by Aminopropylsilatrane Click Chemistry: Superior Antifouling and Biofunctionality

John Andersson, Julia Järlebark, Sriram Kesarimangalam et al
ACS Applied Materials & Interfaces. Vol. 15 (7), p. 10228-10239
Artikel i vetenskaplig tidskrift
2023

Probing physical properties of single amyloid fibrils using nanofluidic channels

Nima Sasanian, Rajhans Sharma, Quentin Lubart et al
Nanoscale. Vol. 15 (46), p. 18737-18744
Artikel i vetenskaplig tidskrift
2023

Label-Free Imaging of Catalytic H<inf>2</inf>O<inf>2</inf> Decomposition on Single Colloidal Pt Nanoparticles Using Nanofluidic Scattering Microscopy

Björn Altenburger, Carl Andersson, Sune Levin et al
ACS Nano. Vol. 17 (21), p. 21030-21043
Artikel i vetenskaplig tidskrift
2022

High diversity of bla<inf>NDM-1</inf>-encoding plasmids in Klebsiella pneumoniae isolated from neonates in a Vietnamese hospital

Sriram Kesarimangalam, Elina Ekedahl, Ngoc Thi Bich Hoang et al
International Journal of Antimicrobial Agents. Vol. 59 (2)
Artikel i vetenskaplig tidskrift
2022

Single-Molecule Trapping and Measurement in a Nanostructured Lipid Bilayer System

Maria Bespalova, Robin Öz, Fredrik Westerlund et al
Langmuir. Vol. 38 (45), p. 13923-13934
Artikel i vetenskaplig tidskrift
2022

Nanofluidic Trapping of Faceted Colloidal Nanocrystals for Parallel Single-Particle Catalysis

Sune Levin, Sarah Lerch, Astrid Boje et al
ACS Nano. Vol. 16 (9), p. 15206-15214
Artikel i vetenskaplig tidskrift
2022

Organic Anisotropic Excitonic Optical Nanoantennas

Evan S.H. Kang, Sriram Kesarimangalam, Inho Jeon et al
Advanced Science. Vol. 9 (23)
Artikel i vetenskaplig tidskrift
2022

HnRNPK maintains single strand RNA through controlling double-strand RNA in mammalian cells

Sagar Mahale, Meenakshi Setia, Bharat Prajapati et al
Nature Communications. Vol. 13 (1), p. 4865-
Artikel i vetenskaplig tidskrift
2022

DNA in Nanochannels - Theory and Applications

Karolin Frykholm, Vilhelm Müller, Sriram Kesarimangalam et al
Quarterly Reviews of Biophysics. Vol. 55
Reviewartikel
2022

Fecal carriage and clonal dissemination of blaNDM-1 carrying Klebsiella pneumoniae sequence type 147 at an intensive care unit in Lao PDR

Tsegaye Sewunet, Sriram Kesarimangalam, Ha Hoang Nguyen et al
PLoS ONE. Vol. 17 (10)
Artikel i vetenskaplig tidskrift
2022

Label-free nanofluidic scattering microscopy of size and mass of single diffusing molecules and nanoparticles

Barbora Spackova, Henrik Klein Moberg, Joachim Fritzsche et al
Nature Methods. Vol. 19 (6), p. 751-758
Artikel i vetenskaplig tidskrift
2022

Quantification of single-strand DNA lesions caused by the topoisomerase II poison etoposide using single DNA molecule imaging

Vandana Singh, Pegah Johansson, Elina Ekedahl et al
Biochemical and Biophysical Research Communications. Vol. 594, p. 57-62
Artikel i vetenskaplig tidskrift
2022

Polyclonal spread of bla<inf>CTX-M-15</inf> through high-risk clones of Escherichia coli at a tertiary hospital in Ethiopia

Tsegaye Sewunet, Daniel Asrat, Yimtubezinash Woldeamanuel et al
Journal of Global Antimicrobial Resistance. Vol. 29, p. 405-412
Artikel i vetenskaplig tidskrift
2022

A simple cut and stretch assay to detect antimicrobial resistance genes on bacterial plasmids by single-molecule fluorescence microscopy

Gaurav Goyal, Elina Ekedahl, My Nyblom et al
Scientific Reports. Vol. 12 (1)
Artikel i vetenskaplig tidskrift
2022

Left versus right: Exploring the effects of chiral threading intercalators using optical tweezers

Adam A. Jabak, Nicholas Bryden, Fredrik Westerlund et al
Biophysical Journal. Vol. 121 (19), p. 3745-3752
Artikel i vetenskaplig tidskrift
2022

Nanofluidics for single DNA molecule analysis of DNA repair

Fredrik Westerlund
Biophysical Journal. Vol. 121 (3), p. 4-4
Övrig text i vetenskaplig tidskrift
2021

Detection of structural variations in densely-labelled optical DNA barcodes: A hidden Markov model approach

Albertas Dvirnas, Callum L. Stewart, Vilhelm Müller et al
PLoS ONE. Vol. 16 (11 November)
Artikel i vetenskaplig tidskrift
2021

C-terminal truncation of α-synuclein alters DNA structure from extension to compaction

Kai Jiang, Sandra Rocha, Ranjeet Kumar et al
Biochemical and Biophysical Research Communications. Vol. 568, p. 43-47
Artikel i vetenskaplig tidskrift
2021

Combining dense and sparse labeling in optical DNA mapping

Erik Torstensson, Gaurav Goyal, Anna Johnning et al
PLoS ONE. Vol. 16 (11 November)
Artikel i vetenskaplig tidskrift
2021

Optical dna mapping of plasmids reveals clonal spread of carbapenem-resistant klebsiella pneumoniae in a large thai hospital

Sriram Kesarimangalam, Tsegaye Sewunet, Walaiporn Wangchinda et al
Antibiotics. Vol. 10 (9)
Artikel i vetenskaplig tidskrift
2021

Complex conformational dynamics of the heart failure‐associated pre‐mirna‐377 hairpin revealed by single‐molecule optical tweezers

Anna Wiktoria Wypijewska Del Nogal, Vinoth Sundar Rajan, Fredrik Westerlund et al
International Journal of Molecular Sciences. Vol. 22 (16)
Artikel i vetenskaplig tidskrift
2021

High prevalence of bla(CTX-M-15) and nosocomial transmission of hypervirulent epidemic clones of Klebsiella pneumoniae at a tertiary hospital in Ethiopia

Tsegaye Sewunet, Daniel Asrat, Yimtubezinash Woldeamanuel et al
JAC-Antimicrobial Resistance. Vol. 3 (1)
Artikel i vetenskaplig tidskrift
2021

CRISPR/CAS9 BASED DNA-COMBING ASSAY FOR DETECTING ANTIMICROBIAL RESISTANCE GENES ON PLASMIDS

Gaurav Goyal, Elina Ekedahl, My Nyblom et al
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, p. 801-802
Paper i proceeding
2021

Single Molecule Experiments Define the Role of Nbs1 and Xrs2 in DNA Tethering by MRN and MRX in DSB Repair

Carl Ivar Möller, Rajhans Sharma, Robin Öz et al
Övrigt konferensbidrag
2021

The HIV-1 nucleocapsid chaperone protein forms locally compacted globules on long double-stranded DNA

Kai Jiang, Nicolas Humbert, Sriram Kesarimangalam et al
Nucleic Acids Research. Vol. 49 (8), p. 4550-4563
Artikel i vetenskaplig tidskrift
2021

Dynamics of Ku and bacterial non-homologous end-joining characterized using single DNA molecule analysis

Robin Öz, Jing L. Wang, Raphael Guerois et al
Nucleic Acids Research. Vol. 49 (5), p. 2629-2641
Artikel i vetenskaplig tidskrift
2021

Mechanical characterization of base analogue modified nucleic acids by force spectroscopy

Vinoth Sundar Rajan, Xavier Viader-Godoy, Yii Lih Lin et al
Physical Chemistry Chemical Physics. Vol. 23 (26), p. 14151-14155
Artikel i vetenskaplig tidskrift
2021

Polyphasic characterization of carbapenemresistant Klebsiella pneumoniae clinical isolates suggests vertical transmission of the bla<inf>KPC-3</inf>gene

Catarina Ferreira, Santosh Kumar Bikarolla, Karolin Frykholm et al
PLoS ONE. Vol. 16 (2 Febuary)
Artikel i vetenskaplig tidskrift
2021

Identity of bla<inf>ctx-m</inf> carrying plasmids in sequential esbl-e. Coli isolates from patients with recurrent urinary tract infections

N. Karami, Sriram Kesarimangalam, Shora Yazdanshenas et al
Microorganisms. Vol. 9 (6)
Artikel i vetenskaplig tidskrift
2021

Shining light on single-strand lesions caused by the chemotherapy drug bleomycin

Vandana Singh, Pegah Johansson, Yii Lih Lin et al
DNA Repair. Vol. 105
Artikel i vetenskaplig tidskrift
2021

Click and Cut: a click chemistry approach to developing oxidative DNA damaging agents

Natasha McStay, Creina Slator, Vandana Singh et al
Nucleic Acids Research. Vol. 49 (18), p. 10289-10308
Artikel i vetenskaplig tidskrift
2021

A parallelized nanofluidic device for high-throughput optical dna mapping of bacterial plasmids

Sriram Kesarimangalam, Yii Lih Lin, Tsegaye Sewunet et al
Micromachines. Vol. 12 (10)
Artikel i vetenskaplig tidskrift
2020

Real-time compaction of nanoconfined DNA by an intrinsically disordered macromolecular counterion

Rajhans Sharma, Sriram Kesarimangalam, Erik D. Holmstrom et al
Biochemical and Biophysical Research Communications. Vol. 533 (1), p. 175-180
Artikel i vetenskaplig tidskrift
2020

Real-Time Condensation of Nanoconfined DNA by an Intrinsically Disordered Polycationic Protein

Rajhans Sharma, Sriram Kesarimangalam, Erik D. Holmstrom et al
Biophysical Journal. Vol. 118 (3)
Paper i proceeding
2020

Lipid vesicle composition influences the incorporation and fluorescence properties of the lipophilic sulphonated carbocyanine dye SP-DiO

Quentin Lubart, Jonas Hannestad, Hudson Pace et al
Physical Chemistry Chemical Physics. Vol. 22 (16), p. 8781-8790
Artikel i vetenskaplig tidskrift
2020

Molecular Epidemiology of OXA-48 and NDM-1 Producing Enterobacterales Species at a University Hospital in Tehran, Iran, Between 2015 and 2016

Hamid Solgi, Shoeib Nematzadeh, Christian G. Giske et al
Frontiers in Microbiology. Vol. 11
Artikel i vetenskaplig tidskrift
2020

A Nanofluidic Device for Multiplexed Analysis of Single Exosomes

Quentin Lubart, Sune Levin, Stephan Block et al
Övrigt konferensbidrag
2020

Cultivation-Free Typing of Bacteria Using Optical DNA Mapping

Vilhelm Müller, My Nyblom, Anna Johnning et al
ACS Infectious Diseases. Vol. 6 (5), p. 1076-1084
Artikel i vetenskaplig tidskrift
2020

Effect of Chirality on the Elastic Properties of the DNA-Threading Binuclear Ruthenium Complex

Adam A. Jabak, Nicholas Bryden, Fredrik Westerlund et al
Biophysical Journal. Vol. 118 (3, Supplement 1), p. 617a-
Paper i proceeding
2020

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication

Ikenna Obi, Matilda Rentoft, Vandana Singh et al
Nucleic Acids Research. Vol. 48 (19), p. 10998-11015
Artikel i vetenskaplig tidskrift
2020

Optical maps of plasmids as a proxy for clonal spread of MDR bacteria: A case study of an outbreak in a rural Ethiopian hospital

Yii Lih Lin, Tsegaye Sewunet, Sriram Kesarimangalam et al
Journal of Antimicrobial Chemotherapy. Vol. 75 (10), p. 2804-2811
Artikel i vetenskaplig tidskrift
2020

Identifying Evolutionarily Conserved Features of NHEJ from Prokaryotes to Eukaryotes using Single-Molecule Approaches

Robin Öz, Rajhans Sharma, Sriram Kesarimangalam et al
Övrigt konferensbidrag
2020

DNA Bridging by the Homologous Recombination Component CtIP Investigated on the Single DNA Molecule Level

Robin Öz, Sriram Kesarimangalam, Fredrik Westerlund
Övrigt konferensbidrag
2020

Quantifying DNA damage induced by ionizing radiation and hyperthermia using single DNA molecule imaging

Vandana Singh, Pegah Johansson, Dmitry Torchinsky et al
Translational Oncology. Vol. 13 (10)
Artikel i vetenskaplig tidskrift
2020

Studying the Intramolecular Forces of Base-Modified Nucleic Acids using Optical Tweezers

Vinoth Sundar Rajan, Xavier Viader, Yii Lih Lin et al
Poster (konferens)
2020

Phosphorylated CtIP bridges DNA to promote annealing of broken ends

Robin Öz, Sean Howard, Rajhans Sharma et al
Proceedings of the National Academy of Sciences of the United States of America. Vol. 117 (35), p. 21403-21412
Artikel i vetenskaplig tidskrift
2019

Multiplexed optical DNA mapping to identify plasmids and their resistance genes in fecal samples

Sriram Kesarimangalam, Yii Lih Lin, Tsegaye Sewunet et al
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, p. 856-857
Paper i proceeding
2019

Genetic variation in the conjugative plasmidome of a hospital effluent multidrug resistant Escherichia coli strain

Catarina Ferreira, D. Bogas, Santosh K. Bikarolla et al
Chemosphere. Vol. 220, p. 748-759
Artikel i vetenskaplig tidskrift
2019

High throughput size-determination and multiplexed fluorescence analysis of single biological particles in a nanofluidic device

Quentin Lubart, Sune Levin, Stephan Block et al
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, p. 1420-1421
Paper i proceeding
2019

Developing an optical DNA mapping toolbox to identify chromosomal translocations in acute myeloid leukemia

Miriam Hitz, Gaurav Goyal, Vilhelm Müller et al
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, p. 626-627
Paper i proceeding
2019

Alpha-Synuclein Binds to DNA and Modulates its Physical Properties

Kai Jiang, Sandra Rocha, Alvina Westling et al
Biophysical Journal
Paper i proceeding
2019

Optical DNA mapping using nanochannels for identification of plasmids carrying carbapenemase blandm-1 gene from patients admitted to a Vietnamese hospital

Sriram Kesarimangalam, Maud Nilsson, Björn Berglund et al
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, p. 805-806
Paper i proceeding
2019

Enzyme-free optical DNA mapping of the human genome using competitive binding

Vilhelm Müller, Albertas Dvirnas, John Andersson et al
Nucleic Acids Research. Vol. 47 (15)
Artikel i vetenskaplig tidskrift
2019

A nanofluidic device for real-time visualization of DNA–protein interactions on the single DNA molecule level

Robin Öz, Sriram Kesarimangalam, Fredrik Westerlund
Nanoscale. Vol. 11 (4), p. 2071-2078
Artikel i vetenskaplig tidskrift
2019

Annealing of ssDNA and compaction of dsDNA by the HIV-1 nucleocapsid and Gag proteins visualized using nanofluidic channels

Kai Jiang, Nicolas Humbert, Sriram Kesarimangalam et al
Quarterly Reviews of Biophysics. Vol. 52, p. e2-e2
Artikel i vetenskaplig tidskrift
2019

A nanofluidic device for parallel single nanoparticle catalysis in solution

Sune Levin, Joachim Fritzsche, Sara Nilsson et al
Nature Communications. Vol. 10 (1)
Artikel i vetenskaplig tidskrift
2019

Bacterial identification by optical mapping of genomic DNA in nanofluidic channels

My Nyblom, Vilhelm Müller, Anna Johnning et al
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, p. 821-822
Paper i proceeding
2019

Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects

Bobo Feng, Robert P. Sosa, Anna Mårtensson et al
Proceedings of the National Academy of Sciences of the United States of America. Vol. 116 (35), p. 17169-17174
Artikel i vetenskaplig tidskrift
2019

Optical DNA Mapping Combined with Cas9-Targeted Resistance Gene Identification for Rapid Tracking of Resistance Plasmids in a Neonatal Intensive Care Unit Outbreak

Santosh Kumar Bikarolla, Viveka Nordberg, Fredrika Rajer et al
mBio. Vol. 10 (4)
Artikel i vetenskaplig tidskrift
2019

Interspecies plasmid transfer appears rare in sequential infections with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae

Anna Lindblom, Sriram Kesarimangalam, Vilhelm Müller et al
Diagnostic Microbiology and Infectious Disease. Vol. 93 (4), p. 380-385
Artikel i vetenskaplig tidskrift
2018

Alpha-Synuclein Modulates the Physical Properties of DNA

Kai Jiang, Sandra Rocha, Alvina Westling et al
Chemistry - A European Journal. Vol. 24 (58), p. 15685-15690
Artikel i vetenskaplig tidskrift
2018

Facilitated sequence assembly using densely labeled optical DNA barcodes: A combinatorial auction approach

Albertas Dvirnas, C. Pichler, Callum L. Stewart et al
PLoS ONE. Vol. 13 (3)
Artikel i vetenskaplig tidskrift
2018

The resistomes of six carbapenem-resistant pathogens - a critical genotype-phenotype analysis

Anna Johnning, N. Karami, Erika Tång Hallbäck et al
Microbial Genomics. Vol. 4 (11)
Artikel i vetenskaplig tidskrift
2018

Hairpins in the conformations of a confined polymer

E. Werner, A. Jain, A. Muralidhar et al
Biomicrofluidics. Vol. 12 (2)
Artikel i vetenskaplig tidskrift
2018

PrgB promotes aggregation, biofilm formation, and conjugation through DNA binding and compaction

Andreas Schmitt, Kai Jiang, Martha I. Camacho et al
Molecular Microbiology. Vol. 109 (3), p. 291-305
Artikel i vetenskaplig tidskrift
2018

A Nanofluidic Device for Real-Time Visualization of DNA-Protein Interactions on the Single DNA Molecule Level

Robin Öz, Sriram Kesarimangalam, Fredrik Westerlund
Biophysical Journal. Vol. 114 (3)
Artikel i vetenskaplig tidskrift
2018

Interactions between DNA and HIV-1 Nucleocapsid Protein Studied using Nanofluidic Channels

Kai Jiang, Nicolas Humbert, Sriram Kesarimangalam et al
Paper i proceeding
2018

Nanofluidic optical DNA mapping for rapid identification of antibiotics resistant plasmids

Yii Lih Lin, Tsegaye Sewunet, Sriram Kesarimangalam et al
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Vol. 3, p. 1822-1825
Paper i proceeding
2018

Bacterial response to graphene oxide and reduced graphene oxide integrated in agar plates

Venkata Raghavendra Subrahmanya Sar Mokkapati, Santosh Pandit, JinHo Kim et al
Royal Society Open Science. Vol. 5 (11)
Artikel i vetenskaplig tidskrift
2018

Reshaping the Energy Landscape Transforms the Mechanism and Binding Kinetics of DNA Threading Intercalation

Andrew G. Clark, M. Nabuan Naufer, Fredrik Westerlund et al
Biochemistry. Vol. 57 (5), p. 614-619
Artikel i vetenskaplig tidskrift
2018

Fluorescence microscopy of nanochannel-confined DNA

Fredrik Westerlund, F. Persson, Joachim Fritzsche et al
Methods in Molecular Biology. Vol. 1665, p. 173-198
Kapitel i bok
2018

Identification of pathogenic bacteria in complex samples using a smartphone based fluorescence microscope

Vilhelm Müller, José M. Sousa, Hatice Ceylan Koydemir et al
RSC Advances. Vol. 8 (64), p. 36493-36502
Artikel i vetenskaplig tidskrift
2018

Stochastic unfolding of nanoconfined DNA: Experiments, model and Bayesian analysis

Jens Krog, Mohammadreza Alizadehheidari, Erik Werner et al
Journal of Chemical Physics. Vol. 149 (21)
Artikel i vetenskaplig tidskrift
2018

Identification and DNA annotation of a plasmid isolated from Chromobacterium violaceum

Daniel C. Lima, Lena Nyberg, Fredrik Westerlund et al
Scientific Reports. Vol. 8 (1)
Artikel i vetenskaplig tidskrift
2018

Vertically Aligned Graphene Coating is Bactericidal and Prevents the Formation of Bacterial Biofilms

Santosh Pandit, Z. Cao, Venkata Raghu Mokkapati et al
Advanced Materials Interfaces. Vol. 5 (7)
Artikel i vetenskaplig tidskrift
2017

Optical DNA mapping in nanofluidic devices: principles and applications

Vilhelm Müller, Fredrik Westerlund
Lab on a Chip - Miniaturisation for Chemistry and Biology. Vol. 17 (4), p. 579-590
Artikel i vetenskaplig tidskrift
2017

Combination of Cold Atmospheric Plasma and Vitamin C Effectively Disrupts Bacterial Biofilms

Santosh Pandit, Venkata Raghavendra Subrahmanya Sar Mokkapati, Saga Helgadottir et al
Clinical microbiology. Vol. 6 (3)
Artikel i vetenskaplig tidskrift
2017

Binding of Thioflavin-T to Amyloid Fibrils Leads to Fluorescence Self-Quenching and Fibril Compaction

David Lindberg, Anna Wenger, Elin Sundin et al
Biochemistry. Vol. 56 (16), p. 2170-2174
Artikel i vetenskaplig tidskrift
2017

Exploring DNA-protein interactions on the single DNA molecule level using nanofluidic tools

Karolin Frykholm, Lena Nyberg, Fredrik Westerlund
Integrative Biology (United Kingdom). Vol. 9 (8), p. 650-661
Artikel i vetenskaplig tidskrift
2017

A nano flow cytometer for single lipid vesicle analysis

R. Friedrich, Stephan Block, Mohammadreza Alizadehheidari et al
Lab on a Chip - Miniaturisation for Chemistry and Biology. Vol. 17 (5), p. 830-841
Artikel i vetenskaplig tidskrift
2017

Efficient surface modification of carbon nanotubes for fabricating high performance CNT based hybrid nanostructures

Nan Wang, Santosh Pandit, L. Ye et al
Carbon. Vol. 111, p. 402-410
Artikel i vetenskaplig tidskrift
2017

Low Concentrations of Vitamin C Reduce the Synthesis of Extracellular Polymers and Destabilize Bacterial Biofilms

Santosh Pandit, Vaishnavi Ravikumar, A. M. Abdel-Haleem et al
Frontiers in Microbiology. Vol. 8 (DEC)
Artikel i vetenskaplig tidskrift
2017

Vitamin C Pretreatment Enhances the Antibacterial Effect of Cold Atmospheric Plasma

Saga Huld Helgadóttir, Santosh Pandit, Venkata Raghu Mokkapati et al
Frontiers in cellular and infection microbiology. Vol. 7 (FEB)
Artikel i vetenskaplig tidskrift
2017

Noise reduction in single time frame optical DNA maps

P. C. Torche, Vilhelm Müller, Fredrik Westerlund et al
PLoS ONE. Vol. 12 (6), p. Article no. e0179041 -
Artikel i vetenskaplig tidskrift
2017

Applications of optical DNA mapping in microbiology

D. Bogas, Lena Nyberg, R. Pacheco et al
BioTechniques. Vol. 62 (6), p. 255-267
Reviewartikel
2016

Rapid Tracing of Resistance Plasmids in a Nosocomial Outbreak Using Optical DNA Mapping

Vilhelm Müller, N. Karami, Lena Nyberg et al
ACS Infectious Diseases. Vol. 2 (5), p. 322-328
Artikel i vetenskaplig tidskrift
2016

DNA compaction by the bacteriophage protein Cox studied on the single DNA molecule level using nanofluidic channels

Karolin Frykholm, Ronnie Berntsson, M. Claesson et al
Nucleic Acids Research. Vol. 44 (15), p. 7219-7227
Artikel i vetenskaplig tidskrift
2016

Dissecting the Dynamic Pathways of Stereoselective DNA Threading Intercalation

A. A. Almaqwashi, Johanna Andersson, Per Lincoln et al
Biophysical Journal. Vol. 110 (6), p. 1255-1263
Artikel i vetenskaplig tidskrift
2016

Role of the Moiety Chirality in Determining the DNA Binding Characteristics of Threading Intercalators

T. Paramanathan, N. Bryden, Fredrik Westerlund et al
Biophysical Journal. Vol. 110 (3), p. 561A-561A
Artikel i vetenskaplig tidskrift
2016

Significance of Steric Bulk in DNA Threading Intercalation Revelaed through Force-Dependent Kinetics

A. G. Clark, T. Paramanathan, Fredrik Westerlund et al
Biophysical Journal. Vol. 110 (3), p. 241A-241A
Artikel i övrig tidskrift
2016

Visualizing the Nonhomogeneous Structure of RAD51 Filaments Using Nanofluidic Channels

Louise Fornander, Karolin Frykholm, Joachim Fritzsche et al
Langmuir. Vol. 32 (33), p. 8403-8412
Artikel i vetenskaplig tidskrift
2016

Single Particle Nanoplasmonic Sensing in Individual Nanofluidic Channels

Joachim Fritzsche, David Albinsson, Michael Fritzsche et al
Nano Letters. Vol. 16 (12), p. 7857-7864
Artikel i vetenskaplig tidskrift
2016

Direct identification of antibiotic resistance genes on single plasmid molecules using CRISPR/Cas9 in combination with optical DNA mapping.

Vilhelm Müller, Fredrika Rajer, Karolin Frykholm et al
Scientific Reports. Vol. 6, p. 37938-
Artikel i vetenskaplig tidskrift
2016

Super-Resolution Genome Mapping in Silicon Nanochannels

J. Jeffet, A. Kobo, T. X. Su et al
ACS Nano. Vol. 10 (11), p. 9823-9830
Artikel i vetenskaplig tidskrift
2016

Detailed characterization of plasmids carrying resistance genes using optical DNA mapping

Vilhelm Müller, Lena Nyberg, Mahmood Saair Quaderi et al
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, p. 1561-1562
Paper i proceeding
2016

DNA intercalation optimized by two-step molecular lock mechanism

A. A. Almaqwashi, Johanna Andersson, Per Lincoln et al
Scientific Reports. Vol. 6, p. 37993-
Artikel i vetenskaplig tidskrift
2016

Rapid identification of intact bacterial resistance plasmids via optical mapping of single DNA molecules

Lena Nyberg, Mahmood Saair Quaderi, Gustav Emilsson et al
Scientific Reports. Vol. 6
Artikel i vetenskaplig tidskrift
2015

A ruthenium dimer complex with a flexible linker slowly threads between DNA bases in two distinct steps

M. Bahira, M. J. McCauley, A. A. Almaqwashi et al
Nucleic Acids Research. Vol. 43 (18), p. 8856-8867
Artikel i vetenskaplig tidskrift
2015

Steady-state and time-resolved Thioflavin-T fluorescence can report on morphological differences in amyloid fibrils formed by A beta(1-40) and A beta(1-42)

David Lindberg, Moa Sandberg Wranne, Melina Gilbert Gatty et al
Biochemical and Biophysical Research Communications. Vol. 458 (2), p. 418-423
Artikel i vetenskaplig tidskrift
2015

Nanoconfined Circular and Linear DNA: Equilibrium Conformations and Unfolding Kinetics

Mohammadreza Alizadehheidari, Erik Werner, C. Noble et al
Macromolecules. Vol. 48 (3), p. 871-878
Artikel i vetenskaplig tidskrift
2015

Extension of nanoconfined DNA: quantitative comparison between experiment and theory

Vitalii Iarko, Erik Werner, Lena Nyberg et al
Physical Review E. Vol. 92 (6), p. Art. Nr. 062701-
Artikel i vetenskaplig tidskrift
2015

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures

Tanmoy Mondal, Santhilal Subhash, Roshan Vaid et al
Nature Communications. Vol. 6, p. art no. 7743-
Artikel i vetenskaplig tidskrift
2015

Two-Step DNA Intercalation by Threading of the Flexible Ruthenium Dimer Studied by the Single Molecule DNA Stretching

I. Rouzina, M. Bahira, A. Almaqwashi et al
Biophysical Journal. Vol. 108 (2), p. 397A-398A
Artikel i övrig tidskrift
2015

Using nanofluidic channels to probe dynamics of RAD51-Filaments

Louise Fornander, Mohammadreza Alizadehheidari, E. Werner et al
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, p. 1826-1828
Paper i proceeding
2015

Hydride formation thermodynamics and hysteresis in individual Pd nanocrystals with different size and shape

Svetlana Syrenova, Carl Wadell, Ferry Nugroho et al
Nature Materials. Vol. 14 (12), p. 1236-1244
Artikel i vetenskaplig tidskrift
2015

Resolving the DNA Binding Mode of a Rotationally Flexible Binuclear Ruthenium Complex

A. A. Almaqwashi, Johanna Andersson, Per Lincoln et al
Biophysical Journal. Vol. 108 (2), p. 396A-396A
Artikel i övrig tidskrift
2015

The Role of the Threading Moiety in DNA Threading Intercalation by Ruthenium Dimer Complexes

A. G. Clark, T. Paramanathan, Fredrik Westerlund et al
Biophysical Journal. Vol. 108 (2), p. 398A-398A
Artikel i övrig tidskrift
2015

Unfolding of nanoconfined circular DNA

Mohammadreza Alizadehheidari, Erik Werner, C Noble et al
Biophysical Journal. Vol. 108 (2 Supplement 1), p. 231A-231A
Artikel i övrig tidskrift
2015

Optical mapping of single DNA molecules in nanochannels: A novel method for identification and characterization of antibiotic resistance

Lena Nyberg, Gustav Emilsson, A. Nilsson et al
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, p. 1045-1047
Paper i proceeding
2015

Evidence for hydrophobic catalysis of DNA strand exchange

Bobo Feng, Fredrik Westerlund, Bengt Nordén
Chemical Communications. Vol. 51 (34), p. 7390-7392
Artikel i vetenskaplig tidskrift
2015

Bacteriophage strain typing by rapid single molecule analysis

A. Grunwald, M. Dahan, A. Giesbertz et al
Nucleic Acids Research. Vol. 43 (18), p. e117-
Artikel i vetenskaplig tidskrift
2015

Fast size-determination of intact bacterial plasmids using nanofluidic channels

Karolin Frykholm, Lena Nyberg, E. Lagerstedt et al
Lab on a Chip - Miniaturisation for Chemistry and Biology. Vol. 15 (13), p. 2739-2743
Artikel i vetenskaplig tidskrift
2014

Amyloid fibrils as dispersing agents for oligothiophenes: control of photophysical properties through nanoscale templating and flow induced fibril alignment

F. G. Backlund, Jens Wigenius, Fredrik Westerlund et al
Journal of Materials Chemistry. Vol. 2 (37), p. 7811-7822
Artikel i vetenskaplig tidskrift
2014

The conquest of middle-earth: combining top-down and bottom-up nanofabrication for constructing nanoparticle based devices

Yuri A. Diaz Fernandez, Tina Gschneidtner, Carl Wadell et al
Nanoscale. Vol. 6 (24), p. 14605-14616
Artikel i vetenskaplig tidskrift
2014

A Versatile Self-Assembly Strategy for the Synthesis of Shape-Selected Colloidal Noble Metal Nanoparticle Heterodimers

Tina Gschneidtner, Yuri A. Diaz Fernandez, Svetlana Syrenova et al
Langmuir. Vol. 30 (11), p. 3041-3050
Artikel i vetenskaplig tidskrift
2014

Single-molecule electronics: from chemical design to functional devices

Lanlan Sun, Yuri A. Diaz Fernandez, Tina Gschneidtner et al
Chemical Society Reviews. Vol. 43 (21), p. 7378-7411
Reviewartikel
2014

Probing Physical Properties of a DNA- Protein Complex Using Nanofluidic Channels

Karolin Frykholm, Mohammadreza Alizadehheidari, Joachim Fritzsche et al
Small. Vol. 10 (5), p. 884-887
Artikel i vetenskaplig tidskrift
2014

Using Nanofluidic Channels to Probe the Dynamics of Rad51-DNA Filaments

Louise Fornander, F. Persson, Joachim Fritzsche et al
Biophysical Journal. Vol. 106 (2), p. 692A-693A
Artikel i övrig tidskrift
2014

Strong DNA deformation required for extremely slow DNA threading intercalation by a binuclear ruthenium complex

A. A. Almaqwashi, T. Paramanathan, Per Lincoln et al
Nucleic Acids Research. Vol. 42 (18), p. 11634-11641
Artikel i vetenskaplig tidskrift
2014

Competitive binding-based optical DNA mapping for fast identification of bacteria - multi-ligand transfer matrix theory and experimental applications on Escherichia coli

A. Nilsson, Gustav Emilsson, Lena Nyberg et al
Nucleic Acids Research. Vol. 42 (15), p. e118-
Artikel i vetenskaplig tidskrift
2014

Quantifying the DNA Binding Kinetics of a Ruthenium Dimer Complex with a Flexible Linker

M. Bahira, M. McCauley, S. Malley et al
Biophysical Journal. Vol. 106 (2), p. 278A-278A
Artikel i övrig tidskrift
2014

Nanoconfined Circular DNA

Mohammadreza Alizadehheidari, E. Werner, C. Noble et al
Övrigt konferensbidrag
2014

Nanoconfined circular DNA

Mohammadreza Alizadehheidari, E. Werner, C. Noble et al
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, p. 1353-1355
Paper i proceeding
2014

Kinetics of DNA Threading Intercalation by a Rigid Ruthenium Complex Dimer

A. A. Almaqwashi, T. Paramanathan, Per Lincoln et al
Biophysical Journal. Vol. 106 (2), p. 277A-277A
Artikel i övrig tidskrift
2014

Sensing Conformational Changes in DNA upon Ligand Binding Using QCM-D. Polyamine Condensation and Rad51 Extension of DNA Layers

Lu Sun, Karolin Frykholm, Louise Fornander et al
Journal of Physical Chemistry B. Vol. 118 (41), p. 11895-11904
Artikel i vetenskaplig tidskrift
2013

Probing the Physical Properties of a DNA-Protein Complex Using Nanofluidic Channels

Mohammadreza Alizadehheidari, Karolin Frykholm, Joachim Fritzsche et al
European Biophysics Journal. Vol. 42, p. S134-S134
Artikel i övrig tidskrift
2013

Assessing How Cationic Intercalators Affect DNA using Nanofluidic Channels

Lena Nyberg, F. Persson, Björn Åkerman et al
Biophysical Journal. Vol. 104 (2), p. 165A-
Poster (konferens)
2013

Turn-On, Fluorescent Nuclear Stains with Live Cell Compatibility

D. R. G. Pitter, Jens Wigenius, A. S. Brown et al
Organic Letters. Vol. 15 (6), p. 1330-1333
Artikel i vetenskaplig tidskrift
2013

Heterogeneous staining: a tool for studies of how fluorescent dyes affect the physical properties of DNA

Lena Nyberg, Fredrik Persson, Björn Åkerman et al
Nucleic Acids Research. Vol. 41 (19), p. articlenr e184-
Artikel i vetenskaplig tidskrift
2013

Base Pair Sensitivity and Enhanced ON/OFF Ratios of DNA-Binding: Donor-Acceptor-Donor Fluorophores

J. Wilson, Jens Wigenius, D. R. G. Pitter et al
Journal of Physical Chemistry B. Vol. 117 (40), p. 12000-12006
Artikel i vetenskaplig tidskrift
2013

What do photons do to fluorescently stained DNA in confinement?

J. P. Beech, Lena Nyberg, Joachim Fritzsche et al
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Freiburg; Germany; 27 October 2013 through 31 October 2013. Vol. 1, p. 5-7
Paper i proceeding
2013

Self-Assembly and Near Perfect Macroscopic Alignment of Fluorescent Triangulenium Salt in Spin-Cast Thin Films on PTFE

Fredrik Westerlund, H. T. Lemke, T. Hassenkam et al
Langmuir. Vol. 29 (22), p. 6728-6736
Artikel i vetenskaplig tidskrift
2013

Quantifying Force-Dependent Binding Kinetics of DNA-Ruthenium Complexes

S. T. Malley, M. J. McCauley, M. Bahira et al
Biophysical Journal. Vol. 104 (2), p. 517A-517A
Poster (konferens)
2013

Probing physical properties of DNA-protein complexes using nanofluidic channels

Karolin Frykholm, Mohammadreza Alizadehheidari, Louise Fornander et al
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Freiburg; Germany; 27 October 2013 through 31 October 2013. Vol. 2, p. 1311-1313
Paper i proceeding
2013

Monomer distributions and intrachain collisions of a polymer confined to a channel

Erik Werner, Fredrik Westerlund, J. O. Tegenfeldt et al
Macromolecules. Vol. 46 (16), p. 6644-6650
Artikel i vetenskaplig tidskrift
2013

Identifying bacteria using DNA binding maps

Gustav Emilsson, A. Nilsson, Lena Nyberg et al
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Freiburg; Germany; 27 October 2013 through 31 October 2013. Vol. 1, p. 473-475
Paper i proceeding
2013

Assessing how cationic intercalators affect DNA using nanofluidic channels

Lena Nyberg, F. Persson, Björn Åkerman et al
European Biophysics Journal. Vol. 42 (S1), p. S202-S202
Artikel i övrig tidskrift
2012

Large area, soft crystalline thin films of N,N ',N ''-trialkyltriazatriangulenium salts with homeotropic alignment of the discotic cores in a lamellar lattice

T. J. Sorensen, C. B. Hildebrandt, Jonas Elm et al
Journal of Materials Chemistry. Vol. 22 (11), p. 4797-4805
Artikel i vetenskaplig tidskrift
2012

A single-step competitive binding assay for mapping of single DNA molecules

Lena Nyberg, Fredrik Persson, J. Berg et al
Biochemical and Biophysical Research Communications. Vol. 417 (1), p. 404-408
Artikel i vetenskaplig tidskrift
2012

Orientational correlations in confined DNA

Erik Werner, Fredrik Persson, Fredrik Westerlund et al
Physical Review E. Vol. 86 (4), p. 041802-
Artikel i vetenskaplig tidskrift
2012

Lipid-Based Passivation in Nanofluidics

Fredrik Persson, Joachim Fritzsche, K. U. Mir et al
Nano Letters. Vol. 12 (5), p. 2260-2265
Artikel i vetenskaplig tidskrift
2012

A lipid-based passivation scheme for nanofluidics

Joachim Fritzsche, F. Persson, K. U. Mir et al
16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012; Okinawa; Japan; 28 October 2012 through 1 November 2012, p. 1876-1878
Paper i proceeding
2012

A hybrid G-quadruplex structure formed between RNA and DNA explains the extraordinary stability of the mitochondrial R-loop

Paulina Wanrooij, Jay Uhler, Yonghong Shi et al
Nucleic Acids Research. Vol. 40 (20), p. 10334-10344
Artikel i vetenskaplig tidskrift
2011

Interactions between a luminescent conjugated polyelectrolyte and amyloid fibrils investigated with flow linear dichroism spectroscopy

Jens Wigenius, Mats Andersson, E. K. Esbjorner et al
Biochemical and Biophysical Research Communications. Vol. 408 (1), p. 115-119
Artikel i vetenskaplig tidskrift
2011

Direct probing of ion pair formation using a symmetric triangulenium dye

Fredrik Westerlund, Jonas Elm, Jacob Lykkebo et al
Photochemical and Photobiological Sciences. Vol. 10 (12), p. 1963-1973
Artikel i vetenskaplig tidskrift
2011

Columnar Self-Assembly and Alignment of Planar Carbenium Ions in Langmuir-Blodgett Films

J. B. Simonsen, Fredrik Westerlund, Dag W. Breiby et al
Langmuir. Vol. 27 (2), p. 792-799
Artikel i vetenskaplig tidskrift
2010

Local conformation of confined DNA studied using emission polarization anisotropy

Fredrik Persson, Fredrik Westerlund, Anders Kristensen et al
NanoBioTech-Montreux 2009
Poster (konferens)
2010

Local conformation of confined DNA studied using emission polarization anisotropy

Fredrik Persson, Fredrik Westerlund, Anders Kristensen et al
Biophysical Society 54th Annual Meeting
Poster (konferens)
2010

DNA strand exchange catalyzed by molecular crowding in PEG solutions

Bobo Feng, Karolin Frykholm, Bengt Nordén et al
Chemical Communications. Vol. 46 (43), p. 8231-8233
Artikel i vetenskaplig tidskrift
2010

Trihydroxytrioxatriangulene—An Extended Fluorescein and a Ratiometric pH Sensor

Fredrik Westerlund, Christoffer B. Hildebrandt, Thomas J. Sörensen et al
Chemistry - A European Journal. Vol. 16 (10), p. 2992-2996
Artikel i vetenskaplig tidskrift
2010

Fluorescence Enhancement of Single DNA Molecules Confined in Si/SiO2 Nanochannels

Fredrik Westerlund, Fredrik Persson, Anders Kristensen et al
Lab on a Chip - Miniaturisation for Chemistry and Biology. Vol. 10 (16), p. 2049-2051
Artikel i vetenskaplig tidskrift
2010

Fluorescence enhancement from single DNA molecules confined in SiO 2 nanochannels

Fredrik Westerlund, Fredrik Persson, A. Kristensen et al
14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010; Groningen; Netherlands; 3 October 2010 through 7 October 2010. Vol. 1, p. 578-580
Paper i proceeding
2010

Fluorescence Enhancement From Single DNA Molecules Confined In Si/SiO2 Nanochannels

Fredrik Westerlund, Fredrik Persson, Anders Kristensen et al
Biophysical Society, 54th Annual Meeting
Poster (konferens)
2009

Mechanism of DNA Strand Exchange at Liposome Surfaces Investigated Using Mismatched DNA

Karolin Frykholm, Bengt Nordén, Fredrik Westerlund
Langmuir. Vol. 25 (3), p. 1606-1611
Artikel i vetenskaplig tidskrift
2008

Complex DNA binding kinetics resolved-by combined circular dichroism and luminescence analysis

Fredrik Westerlund, Pär Nordell, J. Blechinger et al
Journal of Physical Chemistry B. Vol. 112 (21), p. 6688-6694
Artikel i vetenskaplig tidskrift
2008

Enhanced DNA strand exchange on positively charged liposomes

Karolin Frykholm, Francesca Baldelli Bombelli, Bengt Nordén et al
Soft Matter (4), p. 2500 - 2506
Artikel i vetenskaplig tidskrift
2008

DNA Polymorphism as an Origin of Adenine-Thymine Tract Length-Dependent Threading Intercalation Rate

Pär Nordell, Fredrik Westerlund, Anna Reymer et al
Journal of the American Chemical Society. Vol. 130 (44), p. 14651-14658
Artikel i vetenskaplig tidskrift
2008

Finding at-DNA--kinetic recognition of long adenine-thymine stretches by metal-ligand complexes.

Pär Nordell, Fredrik Westerlund, Anna Reymer et al
Nucleic acids symposium series (2004) (52), p. 131-132
Artikel i vetenskaplig tidskrift
2008

Mechanically manipulating the DNA threading intercalation rate

T. Paramanathan, Fredrik Westerlund, M. J. McCauley et al
Journal of the American Chemical Society. Vol. 130 (12), p. 3752-+
Artikel i vetenskaplig tidskrift
2007

Binding geometry and photophysical properties of DNA-threading binuclear ruthenium complexes

Fredrik Westerlund, Mattias P Eng, Mikael Winters et al
Journal of Physical Chemistry B. Vol. 111 (1), p. 310-317
Artikel i vetenskaplig tidskrift
2007

AT-dependent luminescence of DNA-threading ruthenium complexes

Fredrik Westerlund, Per Lincoln
Biophysical Chemistry. Vol. 129 (1), p. 11-17
Artikel i vetenskaplig tidskrift
2007

Kinetic characterization of an extremely slow DNA binding equilibrium

Fredrik Westerlund, Pär Nordell, Bengt Nordén et al
Journal of Physical Chemistry B. Vol. 111 (30), p. 9132-9137
Artikel i vetenskaplig tidskrift
2007

Kinetic recognition of AT-rich DNA by ruthenium complexes

Pär Nordell, Fredrik Westerlund, Marcus Wilhelmsson et al
Angewandte Chemie - International Edition. Vol. 46 (13), p. 2203-2206
Artikel i vetenskaplig tidskrift
2006

DNA Interaction Dynamics of Ruthenium(II) Complexes

Fredrik Westerlund
Doktorsavhandling
2006

Comparing mono- and divalent DNA groove binding cyanine dyes--Binding geometries, dissociation rates, and fluorescence properties

Maja Eriksson, Fredrik Westerlund, Merima Mehmedovic et al
Biophysical Chemistry. Vol. 122 (3), p. 195-205
Artikel i vetenskaplig tidskrift
2005

Monitoring the DNA binding kinetics of a binuclear ruthenium complex by energy transfer: Evidence for slow shuffling

Fredrik Westerlund, Marcus Wilhelmsson, Bengt Nordén et al
Journal of Physical Chemistry B. Vol. 109 (44), p. 21140-21144
Artikel i vetenskaplig tidskrift
2005

Enantioselective luminescence quenching of DNA light-switch [Ru(phen) 2dppz]2+ by electron transfer to structural homologue [Ru(phendione)2dppz]2+

Fredrik Westerlund, F. Pierard, Mattias P Eng et al
Journal of Physical Chemistry B. Vol. 109 (36), p. 17327-17332
Artikel i vetenskaplig tidskrift
2003

Meso stereoisomer as a probe of enantioselective threading intercalation of semirigid ruthenium complex [µ-(11,11'-bidppz)(phen)4Ru2]4+

Marcus Wilhelmsson, Elin Esbjörner Winters, Fredrik Westerlund et al
Journal of Physical Chemistry B. Vol. 107 (42), p. 11784-11793
Artikel i vetenskaplig tidskrift
2003

Micelle-sequestered dissociation of cationic DNA-intercalated drugs: Unexpected surfactant-induced rate enhancement

Fredrik Westerlund, Marcus Wilhelmsson, Bengt Nordén et al
Journal of the American Chemical Society. Vol. 125 (13), p. 3773-3779
Artikel i vetenskaplig tidskrift
2002

DNA-binding of semirigid binuclear ruthenium complex Δ,Δ-[µ-(11,11 '-bidppz)(phen)4Ru2]4+: Extremely slow intercalation kinetics

Marcus Wilhelmsson, Fredrik Westerlund, Per Lincoln et al
Journal of the American Chemical Society. Vol. 124 (41), p. 12092-12093
Artikel i vetenskaplig tidskrift

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Visar 26 forskningsprojekt

2024–2028

Mechanical Characterisation of Nucleic Acids using Single Molecule Methods (MeCHaNiSM)

Fredrik Westerlund Kemisk biologi
Marcus Wilhelmsson Kemi och biokemi
Europeiska kommissionen (EU)

2023–2028

Nanochannel Microscopy for Single Exosome Analysis

Elin Esbjörner Winters Kemisk biologi
Fredrik Westerlund Kemisk biologi
Christoph Langhammer Kemisk fysik
Knut och Alice Wallenbergs Stiftelse

2023–2026

Enkelmolykylanalys av RNA-baserade terapier

Fredrik Westerlund Kemisk biologi
Stiftelsen för Strategisk forskning (SSF)

2023–2025

IDAR-Neo - Identifikation och karaktärisering av tarmbärarskap med antibiotikaresistenta bakterier hos nyfödda i låginkomstländer

Fredrik Westerlund Kemisk biologi
Vetenskapsrådet (VR)

1 publikation finns
2023–2024

Förbättrad diagnos för barn med leukemi genom moderna DNA-analys

Fredrik Westerlund Kemisk biologi
Barncancerfonden

2023–2024

Förbättrad kemoterapi för barn med cancer

Fredrik Westerlund Kemisk biologi
Barncancerfonden

1 publikation finns
2022–2024

Next generationdiagnostics of bacterial infections

Fredrik Westerlund Kemisk biologi
Familjen Erling-Perssons stiftelse

2021–2024

Visualisering av DNA-Reparation - En Molekyl i Taget

Fredrik Westerlund Kemisk biologi
Vetenskapsrådet (VR)

6 publikationer finns
2021–2023

Identifying molecular mechanisms causing sensitivity to chemotherapy

Fredrik Westerlund Kemisk biologi
Cancerfonden

2020–2025

Next Generation Nanofluidic Devices for Single Molecule Analysis of DNA Repair Dynamics

Fredrik Westerlund Kemisk biologi
Europeiska kommissionen (EU)

6 publikationer finns
2020–2022

Förbättrad cancerbehandling av barn känsliga för DNA-skador

Fredrik Westerlund Kemisk biologi
Barncancerfonden

2020–2022

Förbättrad diagnos av akut leukemi hos barn

Fredrik Westerlund Kemisk biologi
Barncancerfonden

2020–2022

Identifiering av bakteriella infektioner och antibiotikaresistens i låginkomstländer via "optical DNA mapping"

Fredrik Westerlund Kemisk biologi
Vetenskapsrådet (VR)

1 publikation finns
2019–2020

Basal oxidative damage level assay (BODLA)

Fredrik Westerlund Kemisk biologi
Vandana Singh Kemisk biologi
Stiftelsen Assar Gabrielssons Fond

2018–2020

Individanpassning av cancerbehandling med cellgifter genom direkt mätning av DNA-skador

Fredrik Westerlund Kemisk biologi
Cancerfonden

2017–2019

A novel ultrafast method for detecting multiresistant bacteria in intensive care units

Fredrik Westerlund Kemisk biologi
Erik Kristiansson Tillämpad matematik och statistik
Familjen Erling-Perssons stiftelse

2017–2019

Mätning av DNA-skador som ett sätt att individanpassa cancerbehandling med cellgifter

Fredrik Westerlund Kemisk biologi
Barncancerfonden

2017–2019

Bärbar diagnostik för sjukdom och antibiotikaresistans med fokus på malaria och bakterieinfektioner

Fredrik Westerlund Kemisk biologi
Vetenskapsrådet (VR)

2016–2018

Characterization of bacterial plasmids on a smartphone

Fredrik Westerlund Kemisk biologi
Bill & Melinda Gates Foundation

2016–2018

Studier av DNA-reparation på enskilda DNA-molekyler

Fredrik Westerlund Kemisk biologi
Stiftelsen Olle Engkvist Byggmästare

1 publikation finns
2015–2019

Genomic diagnostics beyond the sequence (BeyondSeq)

Fredrik Westerlund Kemisk biologi
Europeiska kommissionen (EU)

3 publikationer finns
2015–2016

Odlingsfri identifiering av antibiotikaresistens

Fredrik Westerlund Kemisk biologi
Torsten Söderbergs Stiftelse

2014–2016

Nanofluidics for ultrafast diagnosis of bacterial infections (NanoDiaBac)

Fredrik Westerlund Kemisk biologi
Vetenskapsrådet (VR)

2012–2015

En nanofluidisk plattform för studier av biomolekyler på enkelmolekylnivå

Fredrik Westerlund Fysikalisk kemi
Vetenskapsrådet (VR)

Det kan finnas fler projekt där Fredrik Westerlund medverkar, men du måste vara inloggad som anställd på Chalmers för att kunna se dem.