Orientational correlations in confined DNA
Artikel i vetenskaplig tidskrift, 2012

We study how the orientational correlations of DNA confined to nanochannels depend on the channel diameter D by means of Monte Carlo simulations and a mean-field theory. This theory describes DNA conformations in the experimentally relevant regime where Flory-de Gennes theory does not apply. We show how local correlations determine the dependence of the end-to-end distance of the DNA molecule upon D. Tapered nanochannels provide the necessary resolution in D to study experimentally how the extension of confined DNA molecules depends upon D. Our experimental and theoretical results are in qualitative agreement.

Författare

Erik Werner

Göteborgs universitet

Fredrik Persson

Göteborgs universitet

Fredrik Westerlund

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

J. O. Tegenfeldt

Göteborgs universitet

Bernhard Mehlig

Göteborgs universitet

Physical Review E - Statistical, Nonlinear, and Soft Matter Physics

1539-3755 (ISSN)

Vol. 86 4 041802-

Styrkeområden

Nanovetenskap och nanoteknik

Livsvetenskaper och teknik

Ämneskategorier

Fysik

Biologiska vetenskaper

DOI

10.1103/PhysRevE.86.041802

Mer information

Skapat

2017-10-07