Fluorescence microscopy of nanochannel-confined DNA
Kapitel i bok, 2018

Stretching of DNA in nanoscale confinement allows for several important studies. The genetic contents of the DNA can be visualized on the single DNA molecule level and both the polymer physics of confined DNA and also DNA/protein and other DNA/DNA-binding molecule interactions can be explored. This chapter describes the basic steps to fabricate the nanostructures, perform the experiments and analyze the data.

DNA

Single molecule

Fluorescence

Nanochannels

Författare

Fredrik Westerlund

Chalmers, Biologi och bioteknik, Kemisk biologi

F. Persson

Vanadis Diagnostics

Joachim Fritzsche

Chalmers, Fysik, Kemisk fysik

J. P. Beech

Lunds universitet

J. O. Tegenfeldt

Lunds universitet

Methods in molecular biology (Clifton, N.J.)

1064-3745 (ISSN)

173-198

Ämneskategorier

Kemi

DOI

10.1007/978-1-4939-7271-5_10

Mer information

Senast uppdaterat

2018-03-02