Bacterial response to graphene oxide and reduced graphene oxide integrated in agar plates
Artikel i vetenskaplig tidskrift, 2018

There are contradictory reports in the literature regarding the anti-bacterial activity of graphene, graphene oxide (GO) and reduced graphene oxide (rGO). This controversy is mostly due to variations in key parameters of the reported experiments, like: type of substrate, form of graphene, number of layers, type of solvent and most importantly, type of bacteria. Here, we present experimental data related to bacterial response to GO and rGO integrated in solid agar-based nutrient plates-a standard set-up for bacterial growth that is widely used by microbiologists. Bacillus subtilis and Pseudomonas aeruginosa strains were used for testing bacterial growth. We observed that plate-integrated rGO showed strong anti-bacterial activity against both bacterial species. By contrast, plate-integrated GO was harmless to both bacteria. These results reinforce the notion that the response of bacteria depends critically on the type of graphene material used and can vary dramatically from one bacterial strain to another, depending on bacterial physiology.

graphene oxide

reduced graphene oxide

agar plates


Venkata Raghavendra Subrahmanya Sar Mokkapati

Chalmers, Kemi och kemiteknik, Energi och material

Santosh Pandit

Chalmers, Biologi och bioteknik, Systembiologi

JinHo Kim

Chalmers, Biologi och bioteknik, Systembiologi

Anders Mårtensson

Chalmers, Kemi och kemiteknik, Tillämpad kemi

Martin Lovmar

Wellspect Healthcare

Fredrik Westerlund

Chalmers, Biologi och bioteknik, Kemisk biologi

Ivan Mijakovic

Chalmers, Biologi och bioteknik, Systembiologi

Royal Society Open Science

2054-5703 (eISSN)

Vol. 5 11 181083




Mikrobiologi inom det medicinska området



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