Optical DNA mapping using nanochannels for identification of plasmids carrying carbapenemase blandm-1 gene from patients admitted to a Vietnamese hospital
Paper i proceeding, 2019

Antibiotic misuse has resulted in a rapidly increasing prevalence of multidrug resistant (MDR) bacteria, posing serious threat to human health. Bacterial plasmids play a significant role in spreading antibiotic resistance genes between strains and species. Rapid identification and characterization of plasmids, and knowledge about the presence of resistance genes, thus becomes essential. Here, we use optical DNA mapping (ODM), to identify the plasmid carrying blaNDM-1 gene in samples collected from patients in Vietnam National Children's Hospital (VNCH) in Hanoi, Veitnam, and investigate if a single plasmid is responsible for spreading of the blaNDM-1 gene across different strains of K. pneumonia.

Optical DNA mapping

Plasmids

K. pneumoniae

Antibiotic resistance

Nanofluidics

Visa alla personer

Publicerad i

23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

s. 805-806
9781733419000 (ISBN)

Konferens

23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Basel, Switzerland, 2019-10-26 - 2019-10-30

Kategorisering

Ämneskategorier (SSIF 2011)

Infektionsmedicin

Mikrobiologi

Mikrobiologi inom det medicinska området

Styrkeområden

Hälsa och teknik

Identifikatorer

Mer information

Senast uppdaterat

2024-01-03