HIV-1 viral escape in cerebrospinal fluid of subjects on suppressive antiretroviral treatment.
Artikel i vetenskaplig tidskrift, 2010

Occasional cases of viral escape in cerebrospinal fluid (CSF) despite suppression of plasma human immunodeficiency virus type 1 (HIV-1) RNA have been reported. We investigated CSF viral escape in subjects treated with commonly used antiretroviral therapy regimens in relation to intrathecal immune activation and central nervous system penetration effectiveness (CPE) rank.

Female

Treatment Outcome

HIV Infections

Reverse Transcriptase Polymerase Chain Reaction

isolation & purification

isolation & purification

Male

Anti-HIV Agents

virology

Cerebrospinal Fluid

Cross-Sectional Studies

Viral Load

Plasma

virology

analysis

Viral

Blood-Brain Barrier

Middle Aged

Neopterin

drug therapy

Enzyme-Linked Immunosorbent Assay

virology

RNA

Humans

HIV-1

Författare

Arvid Edén

Göteborgs universitet

Dietmar Fuchs

Medizinische Universitat Innsbruck

Lars Hagberg

Göteborgs universitet

Staffan Nilsson

Göteborgs universitet

Chalmers, Matematiska vetenskaper, matematisk statistik

Serena Spudich

University of California, San Francisco

Bo Svennerholm

Göteborgs universitet

R.W. Price

University of California, San Francisco

Magnus Gisslén

Göteborgs universitet

Journal of Infectious Diseases

0022-1899 (ISSN) 1537-6613 (eISSN)

Vol. 202 1819-25

Ämneskategorier

Infektionsmedicin

PubMed

21050119