Nano Hydroxyapatite-coated Implants Improve Bone Nanomechanical Properties
Artikel i vetenskaplig tidskrift, 2012

Nanostructure modification of dental implants has long been sought as a means to improve osseointegration through enhanced biomimicry of host structures. Several methods have been proposed and demonstrated for creating nanotopographic features; here we describe a nanoscale hydroxyapatite (HA)-coated implant surface and hypothesize that it will hasten osseointegration and improve its quality relative to that of non-coated implants. Twenty threaded titanium alloy implants, half prepared with a stable HA nanoparticle surface and half grit-blasted, acid-etched, and heat-treated (HT), were inserted into rabbit femurs. Pre-operatively, the implants were morphologically and topographically characterized. After 3 weeks of healing, the samples were retrieved for histomorphometry. The nanomechanical properties of the surrounding bone were evaluated by nanoindentation. While both implants revealed similar bone-to-implant contact, the nanoindentation demonstrated that the tissue quality was significantly enhanced around the HA-coated implants, validating the postulated hypothesis.

histology

surfaces

modulus

dogs

calcium phosphate

titanium

nanostructures

biomechanics

tissue

dental implants

mechanical-properties

mineral-content

topography

osseointegration

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Publicerad i

Journal of Dental Research

0022-0345 (ISSN) 15440591 (eISSN)

Vol. 91 Nummer/häfte 12 s. 1172-1177

Kategorisering

Ämneskategorier (SSIF 2011)

Odontologi

Identifikatorer

DOI

10.1177/0022034512463240

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Senast uppdaterat

2018-09-06