Evaluation of bone healing on sandblasted and Acid etched implants coated with nanocrystalline hydroxyapatite: an in vivo study in rabbit femur
Artikel i vetenskaplig tidskrift, 2014

This study aimed at investigating if a coating of hydroxyapatite nanocrystals would enhance bone healing over time in trabecular bone. Sandblasted and acid etched titanium implants with and without a submicron thick coat of hydroxyapatite nanocrystals (nano-HA) were implanted in rabbit femur with healing times of 2, 4, and 9 weeks. Removal torque analyses and histological evaluations were performed. The torque analysis did not show any significant differences between the implants at any healing time. The control implant showed a tendency of more newly formed bone after 4 weeks of healing and significantly higher bone area values after 9 weeks of healing. According to the results from this present study, both control and nano-HA surfaces were biocompatible and osteoconductive. A submicron thick coating of hydroxyapatite nanocrystals deposited onto blasted and acid etched screw shaped titanium implants did not enhance bone healing, as compared to blasted and etched control implants when placed in trabecular bone.

Författare

Lory Melin Svanborg

Göteborgs universitet

Luiz Meirelles

Göteborgs universitet

Victoria Franke Stenport

Göteborgs universitet

Per Kjellin

Promimic AB

F Currie

Promimic AB

Martin Andersson

Chalmers, Kemi- och bioteknik, Teknisk ytkemi

Ann Wennerberg

Göteborgs universitet

International Journal of Dentistry

1687-8728 (ISSN) 1687-8736 (eISSN)

Vol. 2014 197581- 197581

Ämneskategorier

Odontologi

DOI

10.1155/2014/197581

PubMed

24723952