Trithiocyanurate Complexes of Iron, Manganese and Nickel and Their Anticholinesterase Activity
Artikel i vetenskaplig tidskrift, 2014

The complexes of Fe(II), Mn(II) and Ni(II) with a combination of a Schiff base, nitrogen-donor ligand or macrocyclic ligand and trithiocyanuric acid (ttcH(3)) were prepared and characterized by elemental analysis and spectroscopies. Crystal and molecular structures of the iron complex of composition [Fe(L-1)](ttcH(2))(ClO4)center dot EtOH center dot H2O (1), where L-1 is Schiff base derived from tris(2-aminoethyl)amine and 2-pyridinecarboxaldehyde, were solved. It was found that the Schiff base is coordinated to the central iron atom by six nitrogens forming deformed octahedral arrangement, whereas trithiocyanurate(1-) anion, perchlorate and solvent molecules are not coordinated. The X-ray structure of the Schiff base sodium salt is also presented and compared with the iron complex. The anticholinesterase activity of the complexes was also studied.

crystal structure

acetylcholinesterase activity

complexes

trimercaptotriazine

trithiocyanuric acid

Schiff base

Författare

Pavel Kopel

Vysoke Uceni Technicke v Brne, Stredoevropsku Technologicku Institut

Mendelova univerzita v Brne

Karel Dolezal

Univerzita Palackého v Olomouci

Vratislav Langer

Chalmers, Kemi- och bioteknik, Oorganisk miljökemi

D. Jun

Faculty Hospital at Hradec Kralove

Univerzita obrany v Brne

V. Adam

Vysoke Uceni Technicke v Brne, Stredoevropsku Technologicku Institut

Mendelova univerzita v Brne

K. Kuca

Faculty Hospital at Hradec Kralove

R. Kizek

Mendelova univerzita v Brne

Vysoke Uceni Technicke v Brne, Stredoevropsku Technologicku Institut

Molecules

1420-3049 (ISSN)

Vol. 19 4 4338-4354

Ämneskategorier

Oorganisk kemi

DOI

10.3390/molecules19044338