Intraclonal variations among Streptococcus pneumoniae isolates influence the likelihood of invasive disease in children.
Artikel i vetenskaplig tidskrift, 2014

Pneumococcal serotypes are represented by a varying number of clonal lineages with different genetic contents, potentially affecting invasiveness. However, genetic variation within the same genetic lineage may be larger than anticipated.

Antigens

Pneumococcal Infections

Humans

genetics

Carrier State

Streptococcus Phages

Child

Disease Models

Genome

pathology

Child

genetics

Genotype

isolation & purification

Virulence

microbiology

Bacterial

Animal

Genetic Variation

Infant

DNA

epidemiology

epidemiology

Mice

classification

Membrane Proteins

Inbred C57BL

Gel

microbiology

Electrophoresis

Molecular Typing

genetics

Bacterial

Male

analysis

Sequence Analysis

Animals

Pulsed-Field

Female

Mice

analysis

Streptococcus pneumoniae

Adolescent

Preschool

Prophages

Författare

Sarah Browall

Martin Norman

Jeanette Tångrot

Ilias Galanis

Karin Sjöström

Jessica Dagerhamn

Christel Hellberg

Anuj Pathak

Tiziana Spadafina

Andreas Sandgren

Patrick Bättig

Oscar Franzén

Björn Andersson

Åke Örtqvist

Staffan Normark

Birgitta Henriques-Normark

Journal of Infectious Diseases

0022-1899 (ISSN) 1537-6613 (eISSN)

Vol. 209 377-88

Ämneskategorier

Pediatrik

Infektionsmedicin

DOI

10.1093/infdis/jit481

PubMed

24009156