Extracellular water and blood pressure in adults with growth hormone (GH) deficiency: a genotype-phenotype association study.
Artikel i vetenskaplig tidskrift, 2014

Growth hormone deficiency (GHD) in adults is associated with decreased extracellular water volume (ECW). In response to GH replacement therapy (GHRT), ECW increases and blood pressure (BP) reduces or remains unchanged. Our primary aim was to study the association between polymorphisms in genes related to renal tubular function with ECW and BP before and 1 year after GHRT. The ECW measures using bioimpedance analysis (BIA) and bioimpedance spectroscopy (BIS) were validated against a reference method, the sodium bromide dilution method (Br(-)).

Författare

Edna J L Barbosa

Göteborgs universitet

Camilla A M Glad

Göteborgs universitet

Anna G Nilsson

Göteborgs universitet

Niklas Bosaeus

Göteborgs universitet

Helena Filipsson Nyström

Göteborgs universitet

Per-Arne Svensson

Göteborgs universitet

Bengt-Åke Bengtsson

Göteborgs universitet

Staffan Nilsson

Chalmers, Matematiska vetenskaper, matematisk statistik

Göteborgs universitet

Ingvar Bosaeus

Göteborgs universitet

Cesar Luiz Boguszewski

Universidade Federal do Parana

Gudmundur Johannsson

Göteborgs universitet

PLoS ONE

1932-6203 (ISSN)

Vol. 9 8 e105754- e105754

Styrkeområden

Livsvetenskaper och teknik

Ämneskategorier

Annan medicin och hälsovetenskap

DOI

10.1371/journal.pone.0105754

PubMed

25157616