Extracellular water and blood pressure in adults with growth hormone (GH) deficiency: a genotype-phenotype association study.
Artikel i vetenskaplig tidskrift, 2014
Growth hormone deficiency (GHD) in adults is associated with decreased extracellular water volume (ECW). In response to GH replacement therapy (GHRT), ECW increases and blood pressure (BP) reduces or remains unchanged. Our primary aim was to study the association between polymorphisms in genes related to renal tubular function with ECW and BP before and 1 year after GHRT. The ECW measures using bioimpedance analysis (BIA) and bioimpedance spectroscopy (BIS) were validated against a reference method, the sodium bromide dilution method (Br(-)).
Författare
Edna J L Barbosa
Göteborgs universitet
Camilla A M Glad
Göteborgs universitet
Anna G Nilsson
Göteborgs universitet
Niklas Bosaeus
Göteborgs universitet
Helena Filipsson Nyström
Göteborgs universitet
Per-Arne Svensson
Göteborgs universitet
Bengt-Åke Bengtsson
Göteborgs universitet
Staffan Nilsson
Chalmers, Matematiska vetenskaper, Matematisk statistik
Göteborgs universitet
Ingvar Bosaeus
Göteborgs universitet
Cesar Luiz Boguszewski
Universidade Federal do Parana
Gudmundur Johannsson
Göteborgs universitet
Publicerad i
PLoS ONE
1932-6203 (ISSN) 19326203 (eISSN)
Vol. 9 Nummer/häfte 8 s. e105754- art. nr e105754Kategorisering
Styrkeområden
Livsvetenskaper och teknik (2010-2018)
Ämneskategorier (SSIF 2011)
Annan medicin och hälsovetenskap
Identifikatorer
DOI
10.1371/journal.pone.0105754
PubMed
25157616