Robust Controller Design for T1DM Individualized Model: Gain-Scheduling Approach
Artikel i vetenskaplig tidskrift, 2015

This paper deals with the robust gain-scheduled controller design for individualized type 1 diabetes mellitus (T1DM) subject model. The controller is designed using LPV model created from T1DM minimal model with two additional subsystems - absorption of digested carbohydrates and subcutaneous insulin absorption. Data collected from continuous glucose monitoring with the help of pharmacodynamics and pharmacokinetics characteristics were used for model identification. The closed-loop stability and cost for all scheduled parameters is guaranteed by the controller design approach. The benefits of the presented approach are shown in the simulation results.

Robust controller

Output feedback

Quadratic stability

LPV system

Type 1 diabetes mellitus model



Ivan Ottinger

Tomáš Ludwig

Marián Tárník

Vojtech Veselý

Eva Miklovičová

Ján Murgaš

International Review of Automatic Control

1974-6059 (ISSN) 1974-6067 (eISSN)

Vol. 8 155-162