Multifrequency approach in hyperthermia treatment planning: Impact of frequency on SAR distribution in head and neck
Paper i proceeding, 2017

Addition of hyperthermia to radiotherapy has been shown beneficial in management of many types of cancer [1], including Head and Neck tumors [2]. The objective of hyperthermia treatment is to raise the temperature in the tumor to a therapeutic level 40-44°C for typically 60 minutes to achieve cell death or render the cells more sensitive to ionizing radiation and chemical toxins. In our work, we aim to develop H&N applicator that is capable of modifying the focus size according to tumor position and volume. The system consists of a number of antennas placed around a patient, relying on a constructive wave interference to selectively heat the tumour. The spatial control of the foci spot and thus the quality of hyperthermia treatment can be controled by varying operational frequency in addition to amplitude and phase optimization. Due to different wavelengths, treatment associated hot spots often appear at different locations. In conjunction with cooling effect of the blood, the multi-frequency system have potential to achieve higher tumor temperature with 'same' constraints on hot spots. In this paper we investigated if combination of treatment plans utilizing sequential application of various frequencies is superior to the heating with single frequency settings.

Författare

Hana Dobsicek Trefna

Signaler och system, Signalbehandling och medicinsk teknik, Biomedicinsk elektromagnetik

Björn Martinsson

Göteborgs universitet

Chalmers, Matematiska vetenskaper

Therese Petersson

Chalmers, Matematiska vetenskaper

Göteborgs universitet

Niklas Renström

Chalmers, Matematiska vetenskaper

Göteborgs universitet

Mattias Torstensson

Chalmers, Matematiska vetenskaper

Göteborgs universitet

Julia Ravanis

Göteborgs universitet

Chalmers, Matematiska vetenskaper

Petra Kok

Chalmers University of Technology

Mikael Persson

Signaler och system, Signalbehandling och medicinsk teknik, Biomedicinsk elektromagnetik

2017 11th European Conference on Antennas and Propagation, EUCAP 2017

3710-3712

Ämneskategorier

Kommunikationssystem

DOI

10.23919/EuCAP.2017.7928796

ISBN

9788890701870