Taste receptors in the gut - A new target for health promoting properties in diet
Artikel i vetenskaplig tidskrift, 2017

In this review we describe a new target for food functionality, the taste receptors in the gastrointestinal tract. These receptors are involved in an intricate signalling network for monitoring of taste and nutrient intake, homeostasis and energy metabolism, and they are also an early warning system for toxic substances in our diet. Especially the receptors for bitter taste provide a new possibility to activate a number of health related signalling pathways, already at low concentrations of the active substance, without requiring uptake into the body and transport via the circulation. When ligands bind to these receptors, signalling is induced either via peptide hormones into the circulation to other organs in the body, or via nerve fibers directly to the brain.

Taste

Crosstalk

Cell - cell signalling

Functional food

Taste receptors

Författare

Bo Ekstrand

Chalmers, Biologi och bioteknik, Livsmedelsvetenskap

J. F. Young

Aarhus Universitet

M. K. Rasmussen

Aarhus Universitet

Food Research International

0963-9969 (ISSN)

Vol. 100 1-8

Ämneskategorier

Farmakologi och toxikologi

DOI

10.1016/j.foodres.2017.08.024